Results 61 to 70 of about 282,118 (299)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Full degree-of-freedom polarization hologram by freeform exposure and inkjet printing
PhotoniX, 2023 Since the invention of holography by Dennis Gabor, the fabrication of holograms has mainly relied on direct recording of wavefront by engraving the intensity fringes of interfering electric fields into the holographic material. The degree-of-freedom (DoF)
Jianghao Xiong +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
2D tunable graded index prism beam steering device based on nematic liquid crystals [PDF]
, 2011 Liquid crystal devices are being used in many non-display applications in order to construct small devices controlled by low voltage electronics without mechanical components.
Geday, Morten Andreas +4 more
core
Compensation for time fluctuations of phase modulation in a liquid-crystal-on-silicon display by process synchronization in laser materials processing [PDF]
, 2011 We demonstrate the adverse influence of temporal fluctuations of the phase modulation of a spatial light modulator (SLM) display device on nanosecond laser micromachining.
Beck, Rainer J +3 more
core +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Light: Science & Applications, 2022 A tunable liquid crystal grating-based holographic 3D display system is proposed with wide viewing angle and large size.
Yi-Long Li +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Foveated near-eye display for mixed reality using liquid crystal photonics
Scientific Reports, 2020 Foveated near-eye display is one of the most promising approaches to deliver immersive experience of mixed reality. However, it is challenged to conceive a compact optical system.
Seungjae Lee +6 more
doaj +1 more source