QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda +8 more
wiley +1 more source
Aqueous Depolymerization of Polyethylene at Ambient Temperature: <i>In Situ</i> Generation of Permanganate Using Ozone. [PDF]
Behrendt MS +4 more
europepmc +1 more source
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie +7 more
wiley +1 more source
A Multinuclear NMR Study on the Speciation in the Liquid-Phase Synthesis of Sulfide-Based Electrolytes for All-Solid-State Lithium Batteries [PDF]
Agnese Purgatorio +5 more
openalex +1 more source
Positively charged polysilsesquioxane/iodide lonic liquid as a quasi solid‐state redox electrolyte for dye‐sensitized photo electrochemical cells: Infrared, 29Si NMR, and electrical studies [PDF]
Vasko Jovanovski +5 more
openalex +1 more source
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel +16 more
wiley +1 more source
Microwave-assisted synthesis of 2'-hydroxychalcone derivatives in 1-decyl-3-methylimidazolium bromide ionic liquid and its computational study. [PDF]
Auliawati PS +2 more
europepmc +1 more source
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu +4 more
wiley +1 more source
Supramolecular Binding and Extraction of Phosphate, Phosphite and Fluorophosphate Anions from Water by Nanojars. [PDF]
Al Isawi WA +4 more
europepmc +1 more source

