Results 41 to 50 of about 69,963 (260)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Experimental study of liquid spreading in structured packings [PDF]

open access: yes, 2012
Optimization of industrial gas-liquid columns dedicated to CO2 capture requires prediction of liquid distribution within packed beds. In this context, liquid hold-up as well as liquid spreading from a source point have been investigated for Mellapak 250 ...
Roig, Véronique   +2 more
core   +1 more source

UTILITAS PENGOLAHAN LIMBAH CAIR RUMAH SAKIT

open access: yesNalars, 2011
ABSTRAK. Limbah cair adalah hasil buangan berupa cairan yang perlu diolah terlebih dahulu sebelum dibuang. Menteri kesehatan RI telah mengatur melalui keputusan menteri kesehatan Republik Indonesia Nomor : 1204/MENKES/SK/X/2004, Tentang : Persyaratan ...
Permadi Permadi
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

PCF Based Sensor with High Sensitivity, High Birefringence and Low Confinement Losses for Liquid Analyte Sensing Applications [PDF]

open access: yes, 2015
In this paper, we report a design of high sensitivity Photonic Crystal Fiber (PCF) sensor with high birefringence and low confinement losses for liquid analyte sensing applications.
Huseyin Ademgil   +3 more
core   +1 more source

Characteristics of the Liquid Sheet of Air-Induction Spray

open access: yesAgronomy
Spraying remains the primary method of pesticide application in plant protection, and spray drift is one of the important reasons that cause pesticide loss and environmental pollution.
Mingzhi Yan   +3 more
doaj   +1 more source

POSSIBILITIES OF LIQUID AIR TO THE PHYSICIAN. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1901
It is now over a year since I began the use of liquid air in the hospitals of New York, and less than a year since I published in the Medical Record a preliminary report of the results obtained by its use up to that time; and I am led to-day to accept your invitation to present this subject to your Section, no less by the pleasant recollections of the ...
openaire   +2 more sources

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Effect of surfactants on liquid side mass transfer coefficients [PDF]

open access: yes, 2005
In the present paper, the effect of liquid properties (surfactants) on bubble generation phenomenon, interfacial area and liquid side mass transfer coefficient was investigated.
Hebrard, Gilles   +4 more
core   +1 more source

Tunable-Focus Liquid Lens through Charge Injection

open access: yesMicromachines, 2020
Liquid lenses are the simplest and cheapest optical lenses, and various studies have been conducted to develop tunable-focus liquid lenses. In this study, a simple and easily implemented method for achieving tunable-focus liquid lenses was proposed and ...
Shizhi Qian   +3 more
doaj   +1 more source

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