Results 261 to 270 of about 3,019,224 (363)

Cost-effectiveness assessment of liquid biopsy for early detection of lung cancer in Brazil. [PDF]

open access: yesPLoS One
Senna KM   +5 more
europepmc   +1 more source

Avidity‐Based Capture of PD‐L1‐Expressing Exosomes via Dendrimer–Peptide Conjugates: A Nanoengineered Platform for Enhanced Prediction of Immunotherapy Response

open access: yesAdvanced Science, EarlyView.
This study introduces a dendrimer‐peptide conjugate platform (G7‐pPDL1) for avidity‐based capture of PD‐L1‐expressing exosomes. The system exhibits enhanced binding kinetics and exosome capture efficiency, enabling accurate prediction of immunotherapy outcomes.
Jiah Lee   +15 more
wiley   +1 more source

Near‐Infrared‐Responsive Digital PCR‐Assisted Renal Cancer Exosomal miRNAs Insights and Regulation of Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
A near‐infrared‐responsive digital Polymerase Chain Reaction technique with triple‐color coding profiles renal cancer exosomal microRNA biomarkers and their impact on macrophage polarization. Engineered miR‐34‐loaded exosomes via electroporation saturate molecular sponges, downregulating STAT3 in recipient macrophages to prolong M2 polarization. Stable
Lexiang Zhang   +11 more
wiley   +1 more source

MRD4U: A path to development for personalized liquid biopsy for children with central nervous system tumors. [PDF]

open access: yesBMC Cancer
Miller AR   +26 more
europepmc   +1 more source

Globotriaosylceramide Gb3 Influences Wound Healing and Scar Formation by Orchestrating Fibroblast Heterogeneity

open access: yesAdvanced Science, EarlyView.
In superficial second‐degree burn wounds, Gb3 turns on genes related to papillary cells through the FGF2 signaling pathway. This increases the ability of cells to break down fibrin and decreases fibrosis, which ultimately prevents scar formation in burn injuries.
Sujie Xie   +13 more
wiley   +1 more source

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