Results 291 to 300 of about 3,006,723 (410)

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Exosome-Based Liquid Biopsy in Early Screening and Diagnosis of Cancers. [PDF]

Dose Response
Hao X, Liu Z, Ma F, Li T, Liu C, Wang N, Guan J, He N, Liu J, Lu S, Song H, Li J, Wen K.   +12 more
europepmc   +1 more source

Circulating Tumor Cells Shed Shearosome Extracellular Vesicles in Capillary Bifurcations That Activate Endothelial and Immune Cells

Advanced Science, EarlyView.
Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary‐sized bifurcations shed a novel class of shear‐dependent large extracellular vesicle, “shearosomes”, whose proteome comprises of over 3000 distinct proteins.
Angelos Vrynas, Salime Bazban‐Shotorbani, Sara Arfan, Karishma Satia, Brian Cunningham, Gauhar Sagindykova, Mymuna Ashna, Aoyu Zhang, Diana Visan, Aisher Chen, Teige Matthews‐Palmer, Mathew Carter, Fiona Blackhall, Kathryn L. Simpson, Caroline Dive, Paul Huang, Sam H. Au   +16 more
wiley   +1 more source

Liquid Biopsy as a New Tool for Diagnosis and Monitoring in Renal Cell Carcinoma. [PDF]

Cancers (Basel)
Netti GS, De Luca F, Camporeale V, Khalid J, Leccese G, Troise D, Sanguedolce F, Stallone G, Ranieri E.   +8 more
europepmc   +1 more source

Microfluidics for exosome isolation and analysis: enabling liquid biopsy for personalized medicine

, 2017
Jose C. Contreras-Naranjo, Hung‐Jen Wu, Victor M. Ugaz   +2 more
openalex   +2 more sources

Development of a DNA Aptamer‐Based Approach to Noninvasively Image CAR‐T Cells In Vivo and Traceless Enrichment In Vitro

Advanced Science, EarlyView.
A DNA aptamer (A3) with nanomolar affinity for CAR‐T cells is developed via Cell‐SELEX. In Nalm6 tumor‐bearing mice, Cy5‐labeled A3 enables long‐term fluorescence imaging and tracks the biodistribution of CAR‐T cells, with tumor signal peaking on day 14 after CAR‐T cell administration.
Minghui Chen, Pengzhao Chang, Zhen Zhang, Dan Liu, Rui Hou, Ming Shi, Jingjing Li, Kai Xu, Junnian Zheng   +8 more
wiley   +1 more source

Liquid Biopsy Combined with Multi-Omics Approaches in Diagnosis, Management, and Progression of Diabetic Retinopathy. [PDF]

Biomedicines
Chen Q, Chen Y, Mou K, Zhang M.
europepmc   +1 more source

Human papillomavirus in anal biopsy tissues and liquid-based cytology samples of HIV-positive and HIV-negative Thai men who have sex with men

, 2017
Tippawan Pankam, Stephen J. Kerr, Nipat Teeratakulpisan, Piyanee Rodbamrung, Rapeeporn Wongkanya, Somboon Keelawat, Komkrit Ruangritchankul, Piranun Hongchookiat, Ramida Watanapokasin, Nittaya Phanuphak   +9 more
openalex   +1 more source

m6A Modulates RAN Translation From CAG Repeat Expansion RNA

Aggregate, EarlyView.
We described a novel role of N6‐methyladenosine in promoting non‐canonical repeat‐associated non‐AUG translation from CAG repeat expansion RNA. ABSTRACT Nucleotide repeat expansions contribute to the development of a number of neurodegenerative diseases.
Yuxiang Sun, Zhouxian Li, Hui Dai, Yinsheng Wang   +3 more
wiley   +1 more source

The prospects and limitations of liquid biopsy utilization for clinical practice in Taiwan. [PDF]

J Liq Biopsy
Li HY, Chang CC, Yang YH, Yao CY, Chia-Hsun Hsieh J, Chang SH.   +5 more
europepmc   +1 more source