Results 311 to 320 of about 201,821 (348)
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Journal of Precision Oncology, 2022
The molecular landscape of the tumors has been typically established using the surgical or biopsy tissue samples resulting in a sampling bias offering only a single snapshot of tumor heterogeneity from the tissue-based tumor profiles.
Rebecca A. Snyder +2 more
+4 more sources
The molecular landscape of the tumors has been typically established using the surgical or biopsy tissue samples resulting in a sampling bias offering only a single snapshot of tumor heterogeneity from the tissue-based tumor profiles.
Rebecca A. Snyder +2 more
+4 more sources
ACS Applied Bio Materials, 2020
Liquid biopsy allows noninvasive and real-time analysis of tumor-derived circulating targets in body fluids, holding great value for cancer diagnosis, prognosis, personalized therapy, as well as the understanding of mechanisms underlying tumorigenesis and progression.
Lingling Wu +7 more
openaire +2 more sources
Liquid biopsy allows noninvasive and real-time analysis of tumor-derived circulating targets in body fluids, holding great value for cancer diagnosis, prognosis, personalized therapy, as well as the understanding of mechanisms underlying tumorigenesis and progression.
Lingling Wu +7 more
openaire +2 more sources
Liquid Biopsies: Flowing Biomarkers
2022Metastatic dissemination accounts for most of the death in patients during cancer progression. There is thus an urge to identify specific biomarkers as proxies for cancer progression and assessment of treatment efficiency. Cancer is a systemic disease involving the shuttling of tumor cells and tumor secreted factors to distant organs, mostly via ...
Vincent, Hyenne +2 more
openaire +2 more sources
Liquid Biopsy: General Concepts
Acta Cytologica, 2019Liquid biopsy provides the opportunity of detecting, analyzing and monitoring cancer in various body effluents such as blood or urine instead of a fragment of cancer tissue. It is composed of different biological matrices such as circulating tumor cells (CTCs), cell free nucleic acids, exosomes or tumors “educated platelets.” In addition to ...
Poulet, Geoffroy +2 more
openaire +3 more sources
Nature Medicine, 2019
Ultra-deep sequencing of paired plasma-circulating free DNA and white blood cells allows the identification of tumor-derived somatic mutations with high accuracy by filtering out variants consistent with clonal hematopoiesis.
Beatriz, Bellosillo, Clara, Montagut
openaire +2 more sources
Ultra-deep sequencing of paired plasma-circulating free DNA and white blood cells allows the identification of tumor-derived somatic mutations with high accuracy by filtering out variants consistent with clonal hematopoiesis.
Beatriz, Bellosillo, Clara, Montagut
openaire +2 more sources
Science, 2021
Medicine Liquid biopsies, analyses of cell-free DNA that circulates in the blood, can be used in prenatal testing, oncology, and to monitor organ transplant recipients. Lo et al. review the nongenetic information that can be gleaned from analyses of cell-free DNA, which offers additional promise for the applications of this procedure.
openaire +1 more source
Medicine Liquid biopsies, analyses of cell-free DNA that circulates in the blood, can be used in prenatal testing, oncology, and to monitor organ transplant recipients. Lo et al. review the nongenetic information that can be gleaned from analyses of cell-free DNA, which offers additional promise for the applications of this procedure.
openaire +1 more source
Image-Guided Biopsy/Liquid Biopsy
2020Direct tissue sampling is a critical element of cancer care, essential for confirming diagnosis, tumor histology, and staging. Image-guided percutaneous biopsy is the most commonly used technique to procure tumor tissue. Advances in needle design, tissue sampling techniques, and imaging technology have improved the safety and yield of image-guided ...
Rene Roberts +3 more
openaire +1 more source
Liquid biopsy enters the clinic — implementation issues and future challenges
Nature Reviews Clinical Oncology, 2021Michail Ignatiadis +2 more
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