Results 341 to 350 of about 3,006,723 (410)

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

Advanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo, Yen‐Tzu Liao, Hsinyu Lee   +2 more
wiley   +1 more source

Evaluation of microRNAs as liquid biopsy markers in adrenocortical tumors. [PDF]

Front Endocrinol (Lausanne)
Mytareli C, Kalotychou V, Lafioniatis A, Kaltsas G, Zografos GN, Markou A, Papanastasiou L, Fountas A, Vasilliadi DA, Kassi E, Mantzourani M, Angelousi A.   +11 more
europepmc   +1 more source

Quantitative Analysis of Fluorescent Sensor Arrays

Analysis &Sensing, EarlyView.
Fluorescent sensor arrays have great potential for the quantification of analytes in complex systems. Herein, statistical multivariate techniques and deep learning models to provide quantitative information from such arrays are reviewed. Fluorescent sensor arrays address the limitations of a single sensor by leveraging multiple sensing elements to ...
Karandeep Grover, Muhammad Tahir Waseem, Haobo Guo, Elizabeth J. New   +3 more
wiley   +1 more source

International society of liquid biopsy (ISLB) perspective on minimal requirements for ctDNA testing in solid tumors. [PDF]

J Liq Biopsy
Fusco N, Venetis K, Pepe F, Shetty O, Farinas SC, Heeke S, Burnier JV, Patton SJ, Heitzer E, Nigita G, Hofman P, Serrano MJ, Cristofanilli M, Jantus-Lewintre E, Gandara DR, Rolfo C, Malapelle U.   +16 more
europepmc   +1 more source

Functional models from limited data: A parametric and multimodal approach to anatomy and 3D kinematics of feeding in basking sharks (Cetorhinus maximus)

The Anatomical Record, EarlyView.
Abstract Basking sharks, Cetorhinus maximus (Gunnerus, Brugden [Squalus maximus], Det Kongelige Norske Videnskabers Selskabs Skrifter, 1765, vol. 3, pp. 33–49), feed by gaping their mouths and gill slits, greatly reorienting their cranial skeletons to filter food from water.
Tairan Li, Mike Schindler, Martha Paskin, Venkata A. Surapaneni, Elliott Scott, Sabine Hauert, Nicholas Payne, David E. Cade, Jeremy A. Goldbogen, Frederik H. Mollen, Daniel Baum, Sean Hanna, Mason N. Dean   +12 more
wiley   +1 more source

Comparative Analysis of Circulating and Synovial Immune Cells in Early Untreated Rheumatoid Arthritis and their relationship with molecular pathology and disease outcomes

Arthritis &Rheumatology, Accepted Article.
Objectives To assess the relationship of circulating and synovial immune cells with synovial molecular pathology and disease outcomes in early Rheumatoid Arthritis (RA). Methods Early (<12 months) treatment‐naïve RA patients (n=144) from the Pathobiology of Early Arthritis Cohort (PEAC) were included in this posthoc analysis.
Felice Rivellese, Elena Pontarini, Liliane Fossati‐Jimack, Rita A. Moura, Vasco C. Romão, João Eurico Fonseca, Alessandra Nerviani, Cankut Çubuk, Katriona Goldmann, Giovanni Giorli, Myles Lewis, Michele Bombardieri, Costantino Pitzalis, Pathobiology of Early Arthritis Cohort (PEAC) investigators   +13 more
wiley   +1 more source

The latest advances in liquid biopsy for lung cancer-a narrative review. [PDF]

Transl Lung Cancer Res
She W, Garitaonaindia Y, Lin Y.
europepmc   +1 more source

Pharmacokinetics of betamethasone in pre‐eclampsia: An in vivo and ex vivo study

British Journal of Clinical Pharmacology, EarlyView.
Aims To enhance understanding of betamethasone and its metabolites' pharmacokinetics in pregnancy, specifically early‐onset pre‐eclampsia, through a population pharmacokinetic model. Additionally, to investigate the placental metabolism and transfer of betamethasone and its main metabolites.
Sam Schoenmakers, Letao Li, Anna C. M. Kluivers, Michelle Broekhuizen, Madhavi S. Harhangi, A. H. Jan Danser, Irwin Reiss, Karel Allegaert, Sjoerd A. A. van den Berg, Bertrand D. van Zelst, Ron H. N. van Schaik, Philip L. J. DeKoninck, Emma Ronde, Sebastiaan D. T. Sassen, Sinno H. P. Simons, Birgit C. P. Koch   +15 more
wiley   +1 more source

The growing field of liquid biopsy and its Snowball effect on reshaping cancer management. [PDF]

J Liq Biopsy
Borea R, Reduzzi C.
europepmc   +1 more source

The tacrolimus concentration‐to‐dose ratio is associated with kidney function in heart transplant recipients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Heart transplantation (HT) is frequently complicated by chronic kidney disease, of which tacrolimus‐related nephrotoxicity is an important cause. In kidney and liver transplant recipients, fast tacrolimus metabolism (defined as a low concentration‐to‐dose [C0/D] ratio), negatively affects kidney function.
Maaike R. Schagen, Teun B. Petersen, Boris C. A. Seijkens, Jasper J. Brugts, Kadir Caliskan, Alina A. Constantinescu, Brenda C. M. de Winter, Isabella Kardys, Dennis A. Hesselink, Olivier Manintveld   +9 more
wiley   +1 more source