Results 11 to 20 of about 403,538 (154)
Ocrelizumab quantitation by liquid chromatography-tandem mass spectrometry
Journal of Mass Spectrometry and Advances in the Clinical Lab, 2022 Introduction: Ocrelizumab is a monoclonal anti-CD20 antibody approved for the treatment of multiple sclerosis (MS). The clinical value of therapeutic drug monitoring (TDM) for this antibody in treatment of MS is unknown, and an adequately specific and ...
Erik I. Hallin +4 more
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Clinical laboratory use of liquid chromatography mass spectrometry
Türk Biyokimya Dergisi, 2022 Mass spectrometric methods, which transition from chemistry laboratories to clinical laboratories in the basic field, are frequently used in areas such as metabolic analysis, endocrinology, drug research, protein studies and toxicology.
Unlu Ali, Abusoglu Sedat
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Liquid Chromatography–Tandem Mass Spectrometry in Newborn Screening Laboratories
International Journal of Neonatal Screening, 2022 Tandem mass spectrometry (MS/MS) is the most universal platform currently available for the analysis of enzymatic activities and biomarkers in dried blood spots (DBS) for applications in newborn screening (NBS).
Michael H. Gelb +25 more
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Malaysian Cobra Venom: A Potential Source of Anti-Cancer Therapeutic Agents
Toxins, 2019 Cancer is a deadly disease and there is an urgent need for the development of effective and safe therapeutic agents to treat it. Snake venom is a complex mixture of bioactive proteins that represents an attractive source of novel and naturally-derived ...
Syafiq Asnawi Zainal Abidin +3 more
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Metabolites, 2022 Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a standard tool used for absolute quantification of drugs in pharmacokinetic (PK) studies.
Andreas Dannhorn +7 more
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Frontiers in Nutrition, 2023 BackgroundThe misuse of animal-derived stimulants in food is becoming increasingly common, and mass spectrometry (MS) is used extensively for their detection and analysis.
Qiang Zhang, Hongying Du, Yingjian Zhang
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Asian Journal of Pharmaceutical and Clinical Research, 2018 Objective: A simple, rapid high-performance liquid chromatography–mass spectrometry (MS)/MS method was developed for the determination of bisoprolol from confluent Caco-2 monolayers and from aqueous solution.Methods: Chromatography was achieved on discovery C 18, 50 mm×2.1 mm, 5 μm column.
Dmytro Korobko, Liliya Logoyda
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Focal Point: Hyphenated Mass Spectrometry: A. Liquid Chromatography – Mass Spectrometry
CHIMIA, 2003 The identification of unknown compounds is essential in a wide variety of research areas and especially so in environmental analysis. Combining liquid chromatography with tandem mass spectrometry today allows the identification of substances ...
W. Giger
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Cloud point extraction coupled with back extraction: a green methodology in analytical chemistry
Forensic Sciences Research, 2021 Recently, cloud point extraction (CPE) coupled with back extraction (BE) has been suggested as a promising alternative to liquid-liquid extraction. In CPE, non-ionic surfactants in aqueous solutions form micelles and the solution becomes turbid when ...
Shivpoojan Kori
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Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics. [PDF]
, 2018 Novel metabolites distinct from canonical pathways can be identified through the integration of three cheminformatics tools: BinVestigate, which queries the BinBase gas chromatography-mass spectrometry (GC-MS) metabolome database to match unknowns with ...
A El-Tayeb +45 more
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