Results 21 to 30 of about 368,637 (249)

Clinical laboratory use of liquid chromatography mass spectrometry

open access: yesTürk Biyokimya Dergisi, 2022
Mass spectrometric methods, which transition from chemistry laboratories to clinical laboratories in the basic field, are frequently used in areas such as metabolic analysis, endocrinology, drug research, protein studies and toxicology.
Unlu Ali, Abusoglu Sedat
doaj   +1 more source

Liquid Chromatography–Tandem Mass Spectrometry in Newborn Screening Laboratories

open access: yesInternational Journal of Neonatal Screening, 2022
Tandem mass spectrometry (MS/MS) is the most universal platform currently available for the analysis of enzymatic activities and biomarkers in dried blood spots (DBS) for applications in newborn screening (NBS).
Michael H. Gelb   +25 more
doaj   +1 more source

Malaysian Cobra Venom: A Potential Source of Anti-Cancer Therapeutic Agents

open access: yesToxins, 2019
Cancer is a deadly disease and there is an urgent need for the development of effective and safe therapeutic agents to treat it. Snake venom is a complex mixture of bioactive proteins that represents an attractive source of novel and naturally-derived ...
Syafiq Asnawi Zainal Abidin   +3 more
doaj   +1 more source

Correlating Mass Spectrometry Imaging and Liquid Chromatography-Tandem Mass Spectrometry for Tissue-Based Pharmacokinetic Studies

open access: yesMetabolites, 2022
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a standard tool used for absolute quantification of drugs in pharmacokinetic (PK) studies.
Andreas Dannhorn   +7 more
doaj   +1 more source

Recent progress on the detection of animal-derived food stimulants using mass spectrometry-based techniques

open access: yesFrontiers in Nutrition, 2023
BackgroundThe misuse of animal-derived stimulants in food is becoming increasingly common, and mass spectrometry (MS) is used extensively for their detection and analysis.
Qiang Zhang, Hongying Du, Yingjian Zhang
doaj   +1 more source

Focal Point: Hyphenated Mass Spectrometry: A. Liquid Chromatography – Mass Spectrometry

open access: yesCHIMIA, 2003
The identification of unknown compounds is essential in a wide variety of research areas and especially so in environmental analysis. Combining liquid chromatography with tandem mass spectrometry today allows the identification of substances ...
W. Giger
doaj   +1 more source

Cloud point extraction coupled with back extraction: a green methodology in analytical chemistry

open access: yesForensic Sciences Research, 2021
Recently, cloud point extraction (CPE) coupled with back extraction (BE) has been suggested as a promising alternative to liquid-liquid extraction. In CPE, non-ionic surfactants in aqueous solutions form micelles and the solution becomes turbid when ...
Shivpoojan Kori
doaj   +1 more source

Putative multiple reaction monitoring strategy for the comparative pharmacokinetics of postoral administration Renshen–Yuanzhi compatibility through liquid chromatography–tandem mass spectrometry

open access: yesJournal of Ginseng Research, 2020
Background: Exploring the pharmacokinetic (PK) changes of various active components of single herbs and their combinations is necessary to elucidate the compatibility mechanism.
Yufei Sun   +7 more
doaj   +1 more source

Gas-liquid chromatography-mass spectrometry of synthetic ceramides

open access: yesJournal of Lipid Research, 1969
Two series of ceramides with either sphingosine (sphing-4-enine) or sphinganine as base and with one of the saturated fatty acids C16, C18, C20, C22, C24, C26, or oleic acid were analyzed as the 1,3-di-O-trimethylsilyl ether derivatives by gas ...
Bengt Samuelsson, Karin Samuelsson
doaj   +1 more source

State-of-the-Art Analytical Approaches for Illicit Drug Profiling in Forensic Investigations

open access: yesMolecules, 2022
In forensic chemistry, when investigating seized illicit drugs, the profiling or chemical fingerprinting of drugs is considered fundamental. This involves the identification, quantitation and categorization of drug samples into groups, providing ...
Reem Ahmed   +2 more
doaj   +1 more source

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