Results 21 to 30 of about 607,507 (319)

A HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY–MASS SPECTROMETRY/MASS SPECTROMETRY METHOD DEVELOPMENT FOR THE QUANTITATIVE DETERMINATION OF BISOPROLOL FROM CACO-2 CELL MONOLAYERS

open access: yesAsian Journal of Pharmaceutical and Clinical Research, 2018
 Objective: A simple, rapid high-performance liquid chromatography–mass spectrometry (MS)/MS method was developed for the determination of bisoprolol from confluent Caco-2 monolayers and from aqueous solution.Methods: Chromatography was achieved on discovery C 18, 50 mm×2.1 mm, 5 μm column.
Dmytro Korobko, Liliya Logoyda
openaire   +3 more sources

Correlating Mass Spectrometry Imaging and Liquid Chromatography-Tandem Mass Spectrometry for Tissue-Based Pharmacokinetic Studies

open access: yesMetabolites, 2022
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a standard tool used for absolute quantification of drugs in pharmacokinetic (PK) studies.
Andreas Dannhorn   +7 more
doaj   +1 more source

Recent progress on the detection of animal-derived food stimulants using mass spectrometry-based techniques

open access: yesFrontiers in Nutrition, 2023
BackgroundThe misuse of animal-derived stimulants in food is becoming increasingly common, and mass spectrometry (MS) is used extensively for their detection and analysis.
Qiang Zhang, Hongying Du, Yingjian Zhang
doaj   +1 more source

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee   +16 more
wiley   +1 more source

Cloud point extraction coupled with back extraction: a green methodology in analytical chemistry

open access: yesForensic Sciences Research, 2021
Recently, cloud point extraction (CPE) coupled with back extraction (BE) has been suggested as a promising alternative to liquid-liquid extraction. In CPE, non-ionic surfactants in aqueous solutions form micelles and the solution becomes turbid when ...
Shivpoojan Kori
doaj   +1 more source

Mass spectrometry based metabolomics and Lipidomics. [PDF]

open access: yes, 2021
Metabolomics and lipidomics studies are important to understand living organisms at the molecular level. In this dissertation, I conducted various untargeted and targeted metabolomics and lipidomics studies using mass spectrometry based analytical ...
Yuan, Fang
core   +1 more source

Focal Point: Hyphenated Mass Spectrometry: A. Liquid Chromatography – Mass Spectrometry

open access: yesCHIMIA, 2003
The identification of unknown compounds is essential in a wide variety of research areas and especially so in environmental analysis. Combining liquid chromatography with tandem mass spectrometry today allows the identification of substances ...
W. Giger
doaj   +1 more source

Measurement of Trace I-129 Concentrations in CsI Powder and Organic Liquid Scintillator with Accelerator Mass Spectrometry [PDF]

open access: yesNucl.Instrum.Meth.B259:271-276,2007, 2005
Levels of trace radiopurity in active detector materials is a subject of major concern in low-background experiments. Procedures were devised to measure trace concentrations of I-129 in the inorganic salt CsI as well as in organic liquid scintillator with Accelerator Mass Spectrometry (AMS) which leads to improvement in sensitivities by several orders ...
arxiv   +1 more source

CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets.

open access: yesAnalytical Chemistry, 2012
Liquid chromatography coupled to mass spectrometry is routinely used for metabolomics experiments. In contrast to the fairly routine and automated data acquisition steps, subsequent compound annotation and identification require extensive manual analysis
Carsten Kuhl   +4 more
semanticscholar   +1 more source

Low-Afterglow, High-Refractive-Index Liquid Scintillators for Fast-Neutron Spectrometry and Imaging Applications [PDF]

open access: yesIEEE Trans.Nucl.Sci.56:989-993,2009, 2009
For ion and neutron spectrometry and imaging applications at a high intensity pulsed laser facility, fast liquid scintillators with very low afterglow are required. Furthermore, neutron imaging with fiber (or liquid-core) capillary arrays calls for scintillation materials with high refractive index. To this end, we have examined various combinations of
arxiv   +1 more source

Home - About - Disclaimer - Privacy