Results 41 to 50 of about 177,363 (264)

Correlating Mass Spectrometry Imaging and Liquid Chromatography-Tandem Mass Spectrometry for Tissue-Based Pharmacokinetic Studies

Metabolites, 2022
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a standard tool used for absolute quantification of drugs in pharmacokinetic (PK) studies.
Andreas Dannhorn, Emine Kazanc, Gregory Hamm, John G. Swales, Nicole Strittmatter, Gareth Maglennon, Richard J. A. Goodwin, Zoltan Takats   +7 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Determination of Lactoferrin in Camel Milk by Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry Using an Isotope-Labeled Winged Peptide as Internal Standard

Molecules, 2019
An ultrahigh-performance liquid chromatography-tandem mass spectrometry method was developed and validated for the determination of lactoferrin in camel milk based on the signature peptide.
Xia Li, Zengmei Li, Enmin Xu, Ling Chen, Hua Feng, Lu Chen, Ligang Deng, Dongliang Guo   +7 more
doaj   +1 more source

Measurement of Cystine in Urine by Liquid Chromatography–Tandem Mass Spectrometry [PDF]

Clinical Chemistry, 2005
Cystine is a neutral sulfur-containing amino acid involved in a variety of important cellular functions, including detoxification, metabolism, and protein synthesis. Cystine is excreted through the kidneys, with the epithelial cells of the renal proximal tubules absorbing ∼99% of filtered cystine through a high-affinity luminal transport system in the ...
Joanne E, Wear, Brian G, Keevil
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Data supporting the optimization of liquid chromatography tandem mass spectrometry conditions to analyze EPA-priority hormones and bisphenol A in water samples

Data in Brief, 2019
This database presents the optimization of ultra-high-performance liquid chromatography electrospray ionization tandem mass spectrometry (UHPLC-MS/MS) for the analysis of EPA-priority endocrine disruptor compounds (13 hormones and bisphenol A).
Ken Goeury, Sung Vo Duy, Gabriel Munoz, Michèle Prévost, Sébastien Sauvé   +4 more
doaj   +1 more source

Implementation of a MS/MS database for isoquinoline alkaloids and other annonaceous metabolites

Scientific Data, 2022
Measurement(s) electrospray ionization Technology Type(s) Ultra High-performance Liquid Chromatography • Tandem Mass ...
Salemon Akpa Agnès, Timothée Okpekon, Yvette Affoué Kouadio, Adrien Jagora, Dimitri Bréard, Emmanoel V. Costa, Felipe M. A. da Silva, Hector H. F. Koolen, Anne-Marie Le Ray-Richomme, Pascal Richomme, Pierre Champy, Mehdi A. Beniddir, Pierre Le Pogam   +12 more
doaj   +1 more source

Phytochemical Screening of Different Parts of Prangos Platychlaena Boiss by Liquid-Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Eurasian Journal of Science and Engineering, 2021
Liquid-chromatography tandem mass spectrometry (LC-MS/MS) is a hyphenated analytical technique that combines the separating power of liquid chromatography with mass analysis capabilities.
Jwan K. Rahman, Dara M. Jaff, Mehmet Ozdemir, Javed Ahamad, Faiq H.S. Hussain   +4 more
doaj   +1 more source

Drug Screening of Hair by Liquid Chromatography-Tandem Mass Spectrometry [PDF]

Journal of Analytical Toxicology, 2008
Hair has become an important matrix for drug analysis, complementary to blood and urine as a matrix. A prolonged detection window makes hair analysis suitable for the detection of exposure to illegal and medicinal drugs for periods up to 12 months.
S, Hegstad, H Z, Khiabani, L, Kristoffersen, N, Kunøe, P P, Lobmaier, A S, Christophersen   +5 more
openaire   +2 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source