Results 21 to 30 of about 653,696 (267)

Advancements in the characterisation of oligonucleotides by high performance liquid chromatography‐mass spectrometry in 2021: A short review

open access: yesAnalytical Science Advances, 2022
The first oligonucleotide therapeutic was approved by the Food and Drug Administration in 1998, and since then, 12 nucleic acids have been commercialised as medicines.
Fabien Hannauer   +5 more
doaj   +1 more source

Easy Computation of the Various Topologies and Modes of Liquid–Liquid Partition Chromatography by the Theory of Random Walks

open access: yesSeparations, 2021
The article revisits the discrete recurrence method to model the instruments of liquid–liquid partition chromatography as counter-current chromatography (CCC) and centrifugal partition chromatography (CPC).
Frédéric R. Dijoux, Tsvetelina Mandova
doaj   +1 more source

Phytochemical analysis of Panax species: a review

open access: yesJournal of Ginseng Research, 2021
Panax species have gained numerous attentions because of their various biological effects on cardiovascular, kidney, reproductive diseases known for a long time.
Yuangui Yang   +5 more
doaj   +1 more source

Purification of gangliosides by liquid-liquid partition chromatography

open access: yesJournal of Lipid Research, 2008
A liquid-liquid partition chromatographic technique was applied to separate amphiphilic glycolipids. A two-phase solvent system composed of n-butanol-t-butyl methyl ether-acetonitrile-water at a volume ratio of 3:1:1:5 was found to be suitable for ...
Tomohisa Kato, Kenichi Hatanaka
doaj   +1 more source

Preparation characterization and non-isothermal decomposition kinetics of different carbon nitride sheets

open access: yesEgyptian Journal of Petroleum, 2020
Three series of graphitic carbon nitride g-C3N4 namely bulk (BCN), sulfur-doped (SCN) and thin layer (TCN) sheets are prepared using urea precursor under a microwave thermal pyrolysis. Several analytical techniques are used to characterize the obtained g-
M. Elshafie   +3 more
doaj   +1 more source

Research progress in detection technologies of mycotoxins in cereals and cereal-based products

open access: yesShipin yu jixie, 2023
Cereals and cereal-based products are easily polluted by mycotoxins in all aspects of production, storage and transportation, and mycotoxins are difficult to prevent due to their variety, low concentration, strong toxicity andlarge difference in nature ...
NIU Can-jie   +3 more
doaj   +1 more source

Metabolic fingerprinting, antioxidant characterization, and enzyme-inhibitory response of Monotheca buxifolia (Falc.) A. DC. extracts

open access: yesBMC Complementary Medicine and Therapies, 2020
Background Ethnobotanical and plant-based products allow for the isolation of active constituents against a number of maladies. Monotheca buxifolia is used by local communities due to its digestive and laxative properties, as well as its ability to cure ...
Joham Sarfraz Ali   +8 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Novel High-Throughput and Sensitive Electrochemiluminescence Immunoassay System

open access: yesBioengineering
(1) Background: In vitro diagnostic (IVD) tests are the main means of obtaining diagnostic information for clinical purposes. The electrochemiluminescence immunoassay (ECLIA) has become an important in vitro diagnostic technique. It has unique advantages
Xiancheng Liu   +11 more
doaj   +1 more source

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