Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Evaluation of electroosmotic pumping effect in microporous media flow [PDF]
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Li, B +2 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Experimental Study Concerning Mass Transfer Inside the Packed Column of Solar Cooling Liquid Desiccant System Using Counter Flow Configuration [PDF]
Sistem desiccant telah diusulkan sebagai alternatif untuk menghemat energy dibandingkan pendinginudara kompresi uap untuk menangani beban laten. Penggunaan desiccant cair menawarkan beberapakeuntungan desain dan performa dibandingkan desiccant padat ...
Rahmanto, R. H. (R)
core
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Performance study of a novel solar solid dehumidification/regeneration bed for use in buildings air conditioning systems [PDF]
In this paper, a novel solar solid dehumidification/regeneration bed has been proposed, and its three regeneration methods, i.e., simulated solar radiation regeneration, microwave regeneration, and combined regeneration of the microwave and simulated ...
Ding, Zezhi +5 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Optimization of Liquid Desiccant Dehumidifier Performance Using Taguchi Method
An attempt has been made to improve the performance of dehumidifier using liquid desiccant in this study. Experiments have been conducted based on L 16 orthogonal array in order to experimentally investigate the influence of dehumidification process ...
D. Seenivasan, V. Selladurai, P. Senthil
doaj +1 more source
Energy Efficiency in Greenhouse Evaporative Cooling Techniques: Cooling Boxes versus Cellulose Pads [PDF]
Evaporative cooling systems using a combination of evaporative pads and extractor fans require greenhouses to be hermetic. The greatest concentration of greenhouses in the world is located in southeast Spain, but these tend not to be hermetic structures ...
Franco Salas, Antonio +2 more
core +1 more source

