Results 41 to 50 of about 402,989 (257)

EFFICIENCY UPGRADING IN UTILIZATION OF LIQUID-GLASS MIXTURES. PART 2. ELECTROPHYSICAL METHODS OF ACTION

open access: yesЛитьë и металлургия, 2018
The methods of electrophysical influence on the structure of silicate binders and liquid-glass mixtures to improve their properties are generalized. Methods of influence such as ultrasonic, magnetic, electric and electrohydraulic are considered. Of great
A. N. Krutilin   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

OBTAINING CLINKERLESS CEMENTS THROUGH THE SYNTHESIS OF BASIC SOLUTIONS OF SODIUM SILICATE FROM SILICA-CONTAINING ROCKS

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2019
Objectives The creation of clinkerless cements that do not require high-temperature processing and significant natural resources, at the same time as exhibiting good technical parameters, seems to be an important research task.
M. Sh. Salamanova   +3 more
doaj   +1 more source

Investigation of the effect of vacuum on the curing of mixtures on a silicate binder

open access: yesЛитьë и металлургия, 2021
The article presents the results of a study of the effect of vacuuming on the curing processes of liquid‑glass mixtures. The method of conducting experiments using an original laboratory vacuum installation and the mechanisms of curing a liquid‑glass ...
O. A. Rusevich, S. L. Rovin
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Optimization of External Render Formulations Based on Liquid Glass

open access: yesMedžiagotyra, 2013
This work focuses on the adjustment of formulations to determine the influence of the main component quantities on render properties. The purpose of the research is to create external silicate renders with high properties by changing the quantities of ...
Marijonas DAUNORAVIČIUS   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Effects of Annealing on Enthalpy Recovery and Nanomechanical Behaviors of a La-Based Bulk Metallic Glass

open access: yesMetals, 2021
Structural relaxation and nanomechanical behaviors of La65Al14Ni5Co5Cu9.2Ag1.8 bulk metallic glass (BMG) with a low glass transition temperature during annealing have been investigated by calorimetry and nanoindentation measurement.
Ting Shi, Lanping Huang, Song Li
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

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