Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
The non-catalytic DNA polymerase ε subunit is an NPF motif recognition protein. [PDF]
Keskitalo S +10 more
europepmc +1 more source
Highly Entangled Bottlebrush Polymer Networks
Bottlebrush polymers are difficult to entangle, enabling ultrasoft yet brittle networks. We report highly entangled bottlebrush elastomers that remain ultrasoft (∼1 kPa) yet stretch to ∼1800% and exhibit exceptional fatigue resistance. Their intrinsic fatigue strength—fatigue threshold normalized by modulus—surpasses that of highly entangled linear ...
Myoeum Kim +3 more
wiley +1 more source
Application of Imaging Algorithms for Gas-Water Two-Phase Array Fiber Holdup Meters in Horizontal Wells. [PDF]
Li A +8 more
europepmc +1 more source
Field‐programmed anisotropy imparts material‐level intelligence to soft composites. Magnetic torque dynamics drive magneto‐piezoelectric nanowires from random dispersion into deterministic axial alignment. The resulting hierarchical percolation networks confine electromechanical coupling to specific axes and intrinsically decouple superposed force ...
Yubin Kim +9 more
wiley +1 more source
Optimization of oxygen transfer and power consumption in aerobic bioprocess by designing disc turbine impeller based on CFD-Taguchi method. [PDF]
Gu Q +5 more
europepmc +1 more source
In this work, we introduce ancillary‐ligand‐mediated growth control of ultrathin CsPbI3 PeNPLs to achieve highly uniform thickness and reduced agglomeration. Strong ancillary‐ligand coordination to the perovskite surface regulates nucleation and improves surface passivation, enabling color‐pure emission and preferentially oriented superlattices.
Jongbeom Kim +23 more
wiley +1 more source
Field‐Programmable Mobile Magneto‐Photonic Metaparticles for Active Light Manipulation and Steering
We report magneto‐photonic metaparticles that integrate magnetic actuation with nanoimprinted metagratings, enabling mobile and programmable beam steering in aqueous environments. This platform achieves real time, directional light control beyond static or line‐of‐sight systems, while remaining compatible with scalable fabrication, providing a ...
Seung Yeol Lee, Yujie Luo, Ognjen Ilic
wiley +1 more source
Optoelectronic Nanofluidic Neural Networks for Ionic Computing
An ion‐based optoelectronic nanofluidic memristor enables neuromorphic computing in aqueous environments. With tunable ionic memory and multimodal synaptic plasticity, it realizes densely connected ionic neural networks capable of image classification, motion prediction, logic computation, and real‐time in‐sensor computing, advancing fully connected ...
Yaxin Huang +10 more
wiley +1 more source
Comprehensive Analysis of Pressure Drop Phenomena in Rotating Packed Bed Distillation: An In-Depth Investigation. [PDF]
Surmi A, Mohd Shariff A, Lock SSM.
europepmc +1 more source

