Results 31 to 40 of about 935 (257)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Gas-holdup in a 16.6 cm I.D. reciprocating plate column [PDF]

Hemijska Industrija, 2005
The effects of operation conditions (the vibration intensity and gas flow rate) on the gas holdup in a 16.6 cm i.d. two-phase reciprocating plate column (RPC) were studied.
Vasić Ljubiša S., Banković-Ilić Ivana B., Lazić Miodrag L., Veljković Vlada B., Skala Dejan U.   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CFD study and experimental validation of low liquid-loading flow assurance in oil and gas transport: studying the effect of fluid properties and operating conditions on flow variables

Heliyon, 2020
Low liquid-loading flow frequently occurs during the transport of gas products in various industries, such as in the Oil & Gas, the Food, and the Pharmaceutical Industries.
Miguel Ballesteros Martínez, Eduardo Pereyra, Nicolás Ratkovich   +2 more
doaj   +1 more source

Improved Two-Fluid Model for Segregated Flow and Integrated Multiphase Flow Modeling for Downhole Pressure Predictions

Energies, 2023
This work presents an integrated multiphase flow model for downhole pressure predictions with the purpose of producing relatively more accurate predictions under wide-flowing conditions while maintaining a simple form.
Abdullah Alkhezzi, Yilin Fan
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Numerical Simulation of Gas-Liquid Flow in a Bubble Column by Intermittent Aeration in Newtonian Liquid/Non-Newtonian Liquid

International Journal of Chemical Engineering, 2018
The dynamic behaviors of gas-liquid two-phase flow were simulated in a lab-scale intermittent bubble column by Euler-Euler two-fluid model coupled with the PBM (population balance model) using two different liquid phases, i.e., Newtonian fluid (water ...
Zheng Xipeng, Wang Le, Jia Xiaoxuan, Xiang Wenchuan, Yang Shunsheng   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Modeling gas holdup in a multiphase oxygen slurry bubble column reactor for Cu-Cl hydrogen production using CFD

Results in Engineering
The hydrodynamics of the oxygen bubble column reactor is investigated numerically using CFD analyses to predict the values of the gas holdup using Eulerian model and k−ε turbulence method.
M.W. Abdulrahman
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source