Results 61 to 70 of about 408,181 (298)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
EnergiesAs interest in liquid hydrogen (LH2) continues to grow within the energy and mobility sectors, so does the demand for testing capabilities at deep cryogenics temperatures.
Adam Swanger +3 more
doaj +1 more source
Plasma assisted decomposition of methane and propane and cracking of liquid hexadecane [PDF]
, 2014 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityNon-thermal plasmas are considered to be very promising for the initiation of chemical reactions and a vast amount of experimental work has been dedicated to
Aleknaviciute, Irma
core
A model for assessing the risk of liquid hydrogen transport through road tunnels
, 2023 Among the new energy carriers aimed at reducing greenhouse gas emissions, the use of hydrogen is expected to grow significantly in various applications and sectors (i.e., industrial, commercial, transportation, etc.) due to its high energy content by ...
Gianluca Genovese +3 more
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Hydrogen Adsorption on Solid and Liquid Surfaces of Ga–Sn and Ga–In
Advanced Materials InterfacesDynamic liquid metal catalysts have remarkable activity and selectivity toward certain reactions, such as carbon dioxide reduction. The surface hydrogen coverage may play a role in this, including controlling competing reactions such as hydrogen ...
Charlie Ruffman +3 more
doaj +1 more source
Scale-up activation of carbon fibres for hydrogen storage
, 2010 In a previous study, we investigated, at a laboratory scale, the chemical activation of two different carbon fibres (CF), their porosity characterization, and their optimization for hydrogen storage [1]. In the present work, this study is extended to: (i)
Marco Lozar, Juan Pablo +3 more
core +1 more source