Results 61 to 70 of about 2,507,638 (275)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Flow Characteristics and Resistance Coefficient of Liquid Hydrogen in the Ball Valve at Different Opening Degrees

Energies
Hydrogen energy is regarded as an ideal energy source due to its high efficiency, environmental friendliness, and renewability. Liquid hydrogen energy storage is considered a cost-effective method for long-distance transportation and large-volume storage
Jian Xiao, Wei Wang, Jianjun Ye, Jiaxin He   +3 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

An Experimental Study on the Large-Volume Liquid Hydrogen Release in an Open Space

Applied Sciences
Liquid hydrogen is one of the high-quality energy carriers, but a large leak of liquid hydrogen can pose significant safety risks. Understanding its diffusion law after accidental leakage is an important issue for the safe utilization of hydrogen energy.
Zhao Zhang, Gang Lei, Ruofan Sun, Liang Pu, Tianxiang Wang, Wei Dong, Qiang Chen, Qiufan Wei, Mu Liu, Yongchen He, Zhi Zheng, Shengqi Zhang   +11 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Guarded Hot Cylinder Apparatus for Characterization of Thermal Insulation Systems and Materials at Liquid Hydrogen Temperatures

Energies
As interest in liquid hydrogen (LH2) continues to grow within the energy and mobility sectors, so does the demand for testing capabilities at deep cryogenics temperatures.
Adam Swanger, David Creech, Casimir Van Doorne, Andrew Kelly   +3 more
doaj   +1 more source

A Genetic Algorithm Approach to Optimal Sensor Placement in Liquid Hydrogen Fuel Tanks [PDF]

MATEC Web of Conferences
Genetic Algorithms (GAs) offer a robust framework for optimization when vast configuration spaces render analytical methods computationally infeasible.
Winter Adrian, Alijev Ali, Kochan Kay
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Characteristics of liquids lugs in gas–liquid Taylor flow in microchannels [PDF]

, 2012
The hydrodynamics of liquid slugs in gas–liquid Taylor flow in straight and meandering microchannels have been studied using micro Particle Image Velocimetry.
Zaloha, Petr, Kristal, Jiri, Jiricny, Vladimir, Völkel, Norbert, Jiri Kristal, Vladimir Jiricny, Aubin, Joelle, Xuereb, Catherine, Norbert Völkel, Joelle Aubin, Catherine Xuereb, Petr Zaloha   +11 more
core   +1 more source