Results 71 to 80 of about 3,450,982 (278)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Efficiency of semi-automated culture systems on microtubers formation of yam (Dioscorea alata L.) [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2012 Yam clone 'Belep' in temporary immersion system showed favorable results on microtubers formation. Plants cultivated in this type of culture system were the first ones to initiate microtubers formation and produced the highest microtubers number per ...
Jova, MC. +3 more
doaj
Undang-Undang Republik Indonesia Nomor 11 Tahun 2012 Tentang Sistem Peradilan Anak
, 2015 Dalam buku ini terdapat beberapa hal yang dapat kita ketahui bersama meliputi, Acara Peradilan Anak, Petugas Kemasyarakatan, Pidana dan Tindakan, Pelayanan, Perawatan Pendidikan, serta Pembinaan dan Pembinaan Klien ...
Medium
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Growth and Protein Content Establishment of Pleurotus ostreatus on Liquid and Solid Medium
Biosaintifika: Journal of Biology & Biology Education, 2017 Pleurotus ostreatus cultivation is performed using solid medium to harvest fruit body and using liquid medium to harvest mycelia in submerged culture. Modifying nutrients in the medium to increase protein content of the fruitbody and mycelia can be done ...
Aris Mumpuni +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
, 1975 Newspaper publication from Liquid Paper Corporation on Letter Perfect, November 1975, with updates to staff and patrons about the on-goings and news updates regarding the ...
Liquid Paper Corporation
core
Liquid dispersion in packed columns: experiments and numerical modeling [PDF]
, 2013 In order to optimize the design of gas-liquid packed columns used in distillation or in absorption processes, it is of high importance to be able to predict liquid dispersion.
Roig, Véronique +2 more
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source