Results 51 to 60 of about 3,984,547 (275)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

MECHANISMS OF DESTRUCTION AND SYNTHESIS OF LIQUID MEDIA, USED IN THE FOOD INDUSTRY UNDER NON-EQUILIBRIUM CONDITIONS

open access: yesПищевые системы, 2019
The formation of food liquid medium structures containing at least 70 % of disperse particles with high dispersiveness has been considered. The possible formation mechanisms of food liquid medium structure when slow (hydrodynamic) and quick (acoustic ...
T. V. Savenkova   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Selikung Jurnal Medium [PDF]

open access: yes, 2019
Selikung Jurnal ...
Medium, Jurnal
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

CONCENTRATION OF LIQUID PES MEDIA ON THE GROWTH AND PHOTOSYNTHETIC PIGMENTS OF SEAWEEDS COTONII PROPAGULE (KAPPAPHYCUS ALVAREZII DOTY) THROUGH TISSUE CULTURE [PDF]

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2018
In vitro tissue culture of Kappaphycus alvarezii, the required nutrients are derived from the culture medium. The use of liquid PES medium as a culture medium has been widely applied to increase the growth rate of seaweeds.
Lumbessy S.Y.   +3 more
doaj   +1 more source

Numerical study of the process of unsteady flow in a three-layer porous medium

open access: yesMagazine of Civil Engineering, 2023
The unsteady fluid flow in a three-layer porous medium is numerically investigated and is an important and topical problem. An analytical solution of the equation for the pressure fluid layer is obtained on the basis of the theory of elastic regime ...
Ravshanov Normahmad   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

CHANGE OF MECHANICAL PROPERTIES OF THIN-LAYER MEMBRANES UNDER THE INFLUENCE OF LIQUID MEDIUM

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2017
Thin-layer membranes and membrane compositions find application in different indus- tries as independent design elements and as coatings. With the development of new technolo- gies, functional coatings are become increasingly widespread.
SAMAT NUKHOVICH YAKUPOV   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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