Results 51 to 60 of about 3,981,852 (275)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The formation of food liquid medium structures containing at least 70 % of disperse particles with high dispersiveness has been considered. The possible formation mechanisms of food liquid medium structure when slow (hydrodynamic) and quick (acoustic ...
T. V. Savenkova +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Numerical study of the process of unsteady flow in a three-layer porous medium
The unsteady fluid flow in a three-layer porous medium is numerically investigated and is an important and topical problem. An analytical solution of the equation for the pressure fluid layer is obtained on the basis of the theory of elastic regime ...
Ravshanov Normahmad +3 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
CONCENTRATION OF LIQUID PES MEDIA ON THE GROWTH AND PHOTOSYNTHETIC PIGMENTS OF SEAWEEDS COTONII PROPAGULE (KAPPAPHYCUS ALVAREZII DOTY) THROUGH TISSUE CULTURE [PDF]
In vitro tissue culture of Kappaphycus alvarezii, the required nutrients are derived from the culture medium. The use of liquid PES medium as a culture medium has been widely applied to increase the growth rate of seaweeds.
Lumbessy S.Y. +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
CHANGE OF MECHANICAL PROPERTIES OF THIN-LAYER MEMBRANES UNDER THE INFLUENCE OF LIQUID MEDIUM
Thin-layer membranes and membrane compositions find application in different indus- tries as independent design elements and as coatings. With the development of new technolo- gies, functional coatings are become increasingly widespread.
SAMAT NUKHOVICH YAKUPOV +2 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source

