Results 31 to 40 of about 1,387,763 (307)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Mount makes liquid nitrogen-cooled gamma ray detector portable [PDF]
, 1966 Liquid nitrogen-cooled gamma ray detector system is made portable by attaching the detector to a fixture which provides a good thermal conductive path between the detector and the liquid nitrogen in a dewar flask and a low heat leak path between the ...
Fessler, T. E.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Titan's past and future: 3D modeling of a pure nitrogen atmosphere and geological implications
, 2014 Several clues indicate that Titan's atmosphere has been depleted in methane during some period of its history, possibly as recently as 0.5-1 billion years ago. It could also happen in the future.
Charnay, Benjamin +4 more
core +3 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The effect of liquid nitrogen cooling on coal cracking and mechanical properties
Energy Exploration & Exploitation, 2018 Liquid nitrogen is a type of super-cryogenic fluid, which can cause the reservoir temperature to decrease significantly and thereby induce formation rock damage and cracking when it is injected into the wellbore as fracturing fluid.
Chengzheng Cai, Feng Gao, Yugui Yang
doaj +1 more source
The boiling suppression of liquid nitrogen
, 2009 When He gas is injected from room temperature into boiling liquid N$_{2}$, boiling is suppressed, leaving liquid surface flat like a mirror. Although the qualitative explanation for this phenomenon is known [Minkoff G J \textit{et al}.
H. Fukuyama +5 more
core +1 more source