Results 41 to 50 of about 1,387,763 (307)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Investigation of Rock Mechanical Properties under Liquid Nitrogen Environment

open access: yesGeofluids, 2023
In order to promote sustainable energy development and reduce the impact of fossil fuels on the environment, it is crucial to strengthen the development and utilization of clean and renewable geothermal energy.
Linchao Wang   +5 more
doaj   +1 more source

Partial discharge in liquid nitrogen

open access: yesElectrical Engineering in Japan, 1976
Results are presented of experiments on partial discharge in liquid nitrogen, including insulation breakdown characteristics of liquid nitrogen, partial discharge characteristics of composite insulation systems, lifetime of polymer films, impulse breakdown of polymer films in liquid nitrogen, etc.
Masamitsu Kosaki   +3 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Metaheuristic algorithm for parametric optimization of liquid nitrogen pumping in hydrocarbon and allied fluids piping systems [PDF]

open access: yesEngineering and Technology Journal
This study applied a population-based metaheuristic algorithm to optimize liquid nitrogen pumping in hydrocarbon and allied fluids piping systems to ensure optimal process efficiency, minimize energy consumption, and minimize operational costs without ...
S. Isaac, C. Kadurumba, H. Ugwu, F. Abam
doaj   +1 more source

Front Cover [PDF]

open access: yes, 2006
Todd Curtis ‘07 uses liquid nitrogen during an experiment to measure the efficiency of a solar ...
Ballard, Tom
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The water-cryogen heat exchanger [PDF]

open access: yes, 1970
Heat exchanger, using water as heat medium, converts liquid hydrogen to gaseous hydrogen at a very high rate. Possible applications include treatment of liquified natural gas in cities to bring the gas on-line quickly, conversion of liquid oxygen and ...
Bartlit, J. R.   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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