Results 41 to 50 of about 7,786 (254)

e- discrimination at high energy in the JUNO detector [PDF]

EPJ Web of Conferences, 2019
Cosmic Ray and neutrino oscillation physics can be studied by using atmospheric neutrinos. JUNO (Jiangmen Underground Neutrino Observatory) is a large liquid scintillator detector with low energy detection threshold and excellent energy resolution.
Settanta Giulio, Maria Mari Stefano, Martellini Cristina, Montini Paolo   +3 more
doaj   +1 more source

A Novel Portable Device For Gamma And Neutron Spectroscopy With Special Nuclear Material Identification [PDF]

EPJ Web of Conferences, 2020
The development of new types of detectors and the increased performance of the electronics have paved the way for developing advanced systems for the measurement and identification of radioactive material that can be involved, for example, in illicit ...
Morichi Massimo, Fanchini Erica, Mangiagalli Giacomo   +2 more
doaj   +1 more source

Optimization of Liquid Scintillator Composition [PDF]

, 2017
Nowadays, many particle detectors use liquid scintillator (LS) as a detection medium. In particular, Water-based Liquid Scintillator (WbLS) that is a new material currently under development. It is based on the idea of dissolving the organic scintillator
Batyrkhanov, Ayan
core  

Towards 14C-free liquid scintillator

, 2017
A series of measurements has been started where the 14C concentration is determined from several liquid scintillator samples. A dedicated setup has been designed and constructed with the aim of measuring concentrations smaller than 10−18.
Krokhaleva, S, Sinev, V V, Grishina, V. Yu., Loo, Kai, V V Kazalov, Trzaska, Wladyslaw, Virkaj arvi, A., V Yu Grishina, Umerov, Sh. I., W H Trzaska, Kuzminov, V. V., Kazalov, V V, Kuusiniemi, P., Novikova, G. Y., Gangapshev, A M, Yanovich, Y. A., V V Sinev, Virkajärvi, A, B K Lubsandorzhiev, Lubsandorzhiev, B. K., V V Kuzminov, Novikova, G Y, Morgalyuk, V P, I R Barabanov, L B Bezrukov, Hissa, J, T Enqvist, Sinev, V. V., Joutsenvaara, J, Krokhaleva, S., S Krokhaleva, Gavrilyuk, Y M, A M Pshukov, Enqvist, T, Zavarzina, V. P., Lubsandorzhiev, B K, Kurlovich, A. S., J Joutsenvaara, Kurlovich, A S, V I Gurentsov, Kazalov, V. V., Barabanov, R, J Hissa, Grishina, V Yu, Bezrukov, L B, Veresnikova, A V, Enqvist, T., Slupecki, Maciej, A Virkajärvi, Gavrilyuk, Y. M., Pshukov, A. M., Veresnikova, A. V., Morgalyuk, V. P., Kutuniva, J, M S lupecki, Sh I Umerov, Umerov, Sh I, A M Gangapshev, Y M Gavrilyuk, Loo, K, Trzaska, W H, Kuusiniemi, P, J Kutuniva, Lubsandorzhiev, S, Słupecki, M, Gurentsov, V. I., Kutuniva, J., Bezrukov, L. B., Barabanov, I. R., Gurentsov, V I, K Loo, Joutsenvaara, J., V P Zavarzina, Gangapshev, A. M., P Kuusiniemi, A V Veresnikova, Zavarzina, V P, G Y Novikova, Hissa, J., Yanovich, Y A, V P Morgalyuk, Kuzminov, V V, S Lubsandorzhiev, Pshukov, A M, Y A Yanovich, Lubsandorzhiev, S., A S Kurlovich   +86 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Positively Charged Polymer‐Brush MOFs for Large‐Area, Pressure‐Resistant Gas Separation Membranes

Advanced Materials, EarlyView.
A universal POPA strategy enables positively charged polymer‐brush MOFs with self‐adaptive interfacial interlocking to resist aggregation under fast processing. This design ensures seamless dispersion within large‐area selective layers, achieving 1 m‐wide roll‐to‐roll fabrication of pressure‐resistant MMCMs with tunable CO2 separation performance ...
Yi Yang, Ye Yuan, Yuxiu Sun, Fei Shi, Chenyang Song, Weifan Wang, Qinghua Li, Menglong Sheng, Zhihua Qiao, Jingwei Hou, Anthony K. Cheetham, Zhi Wang   +11 more
wiley   +1 more source

Advances in Halide Perovskites for Photon Radiation Detectors

Advanced Materials Technologies, EarlyView.
This work highlights recent progress in perovskite‐based photon radiation detectors, covering organic–inorganic hybrid, inorganic, lead‐free double, and vacancy‐ordered halide perovskites. Their detection performance is compared, material‐specific advantages and challenges are examined, and provides insight into current limitations and future ...
Liangling Wang, Jieqi Wang, Xiaojun Cui, Carsten Ronning   +3 more
wiley   +1 more source

Liquid scintillator tiles for calorimetry

, 2016
Future experiments in high energy and nuclear physics may require large, inexpensive calorimeters that can continue to operate after receiving doses of 50 Mrad or more. The light output of liquid scintillators suffers little degradation under irradiation.
Wetzel, J, Pedro, K., Barbaro, P De, Rumerio, Paolo, Hatakeyama, K., Samuel, J, Amouzegar, M., Hirschauer, J, Sharp, E, Hatakeyama, K, Amouzegar, M, Yang, Z., Pastika, N J, Shin, Y. H., Yao, Y, Vishnevskiy, D., Belloni, A., Calderon, J., Vishnevskiy, D, Samuel, J., Wetzel, J., Tiras, E, Jeng, G. Y., Hirschauer, J., Sharp, E., Yang, Z, Youn, S. W., Bilki, B, Youn, S W, Bilki, B., Belloni, A, Tiras, EMRAH, Yao, Y., Jeng, G Y, Eno, S C, De Barbaro, P., Pedro, K, Shin, Y H, Calderon, J, Pastika, N. J., Eno, S. C.   +40 more
core   +1 more source