Results 51 to 60 of about 2,699,522 (296)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Dynamics of droplets on a thin [EMIm]Ac ionic liquid film

e-Prime: Advances in Electrical Engineering, Electronics and Energy, 2023
The impact of water and 1-ethyl-3-methylimidazolium acetate ([EMIm]Ac) drops on [EMIm]Ac ionic liquid film was studied. The hydrodynamics of the impact of drops on a water liquid film were compared.
Fangfang Zhang, Zhen Shen, Geng Chen, Shuyan Che   +3 more
doaj   +1 more source

Structural Properties of High and Low Density Water in a Supercooled Aqueous Solution of Salt

, 2011
We consider and compare the structural properties of bulk TIP4P water and of a sodium chloride aqueous solution in TIP4P water with concentration c = 0.67 mol/kg, in the metastable supercooled region. In a previous paper [D. Corradini, M.
Corradini, D., Gallo, P., Rovere, M.
core   +1 more source

SAFT-γ force field for the simulation of molecular fluids: 4. A single-site coarse-grained model of water applicable over a wide temperature range [PDF]

, 2014
In this work, we develop coarse-grained (CG) force fields for water, where the effective CG intermolecular interactions between particles are estimated from an accurate description of the macroscopic experimental vapour-liquid equilibria data by means of
Avendaño, C, Avendaño, C, Jackson, G, Lafitte, T, Lafitte, T, Lobanova, O, Müller, EA   +6 more
core   +2 more sources

Tuning Water Networks via Ionic Liquid/Water Mixtures [PDF]

International Journal of Molecular Sciences, 2020
Water in nanoconfinement is ubiquitous in biological systems and membrane materials, with altered properties that significantly influence the surrounding system. In this work, we show how ionic liquid (IL)/water mixtures can be tuned to create water environments that resemble nanoconfined systems.
Archana Verma, John P. Stoppelman, Jesse G. McDaniel   +2 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Equation of State of Supercooled Water from the Sedimentation Profile [PDF]

, 2002
To study the coexistence of two liquid states of water within one simulation box, we implement an equilibrium sedimentation method--which involves applying a gravitational field to the system and measuring/calculating the resulting density profile in ...
Sciortino, F., Stanley, H. E., Yamada, M.   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Properties of New Flows Indicate that Martian Gullies Form via CO2 Frost‐Fluidization Processes

Geophysical Research Letters
Martian gully landforms are widely seen as evidence of liquid water, often attributed to snowmelt during high‐obliquity periods within the last few million years.
Colin M. Dundas, Susan J. Conway, Kelly Pasquon, Axel Noblet, Lonneke Roelofs   +4 more
doaj   +1 more source

Molecular dynamics study of accelerated ion-induced shock waves in biological media [PDF]

, 2016
We present a molecular dynamics study of the effects of carbon- and iron-ion induced shock waves in DNA duplexes in liquid water. We use the CHARMM force field implemented within the MBN Explorer simulation package to optimize and equilibrate DNA ...
A.D. MacKerell Jr., A.V. Yakubovich, Andrey V. Solov’yov, B. Boudaïffa, D. Bottländer, D. Schardt, E. Surdutovich, E. Surdutovich, E. Surdutovich, E. Surdutovich, F. Pan, Fred J. Currell, G.B. Sushko, H. Qiu, H.M. Berman, I.A. Solov’yov, J.S. Loeffler, M. Scholz, Nigel J. Mason, O.I. Obolensky, P. de Vera, P. de Vera, Pablo de Vera, T.J. Robbins, U. Heinemann, W. Humphrey   +25 more
core   +4 more sources