Results 1 to 10 of about 744 (111)
Atg8 family proteins, LIR/AIM motifs and other interaction modes
The Atg8 family of ubiquitin-like proteins play pivotal roles in autophagy and other processes involving vesicle fusion and transport where the lysosome/vacuole is the end station. Nuclear roles of Atg8 proteins are also emerging.
Terje Johansen
exaly +2 more sources
The crystal structure of mouse LC3B in complex with the FYCO1 LIR reveals the importance of the flanking region of the LIR motif [PDF]
FYVE and coiled-coil domain-containing protein 1 (FYCO1), a multidomain autophagy adaptor protein, mediates microtubule plus-end-directed autophagosome transport by interacting with kinesin motor proteins and with the autophagosomal membrane components microtubule-associated protein 1 light chain 3 (LC3), Rab7 and phosphatidylinositol 3-phosphate (PI3P)
Taisuke Tomita, Shimizu Toshiyuki
exaly +3 more sources
The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes [PDF]
The MHC class I binding proteins leukocyte immunoglobulin-like receptor (LIR)-1 and -2 recognize a similar broad spectrum of HLA-A, -B and -C alleles but are differentially expressed in lymphocytes, monocytes, and dendritic cells. In monocytes, phosphorylation of LIR-1 and LIR-2 results in the binding of the tyrosine phosphatase SHP-1.
David Cosman, C R Maliszewski
exaly +3 more sources
INTERTEKSTUAL TEMBANG TRADISIONAL JAWA LIR-ILIR DALAM PUISI INDONESIA MODERN
ABSTRAK: Penelitian ini bertujuan untuk mengetahui bentuk pemaknaan terhadap tembang tradisional Jawa Lir-ilir dalam bentuk puisi Indonesia modern. Data penelitian berupa teks tembang tradisional Jawa Lir ilir karya Sunan Kalijaga, puisi berjudul Lir ...
Achmad Sultoni
doaj +1 more source
Background: People forced to leave their homes, such as refugees and internally displaced persons, are exposed to various stressors during their forced displacement, putting them at risk for mental disorders.
Sarah K. Schäfer +6 more
doaj +1 more source
Preparation and properties of liquid polyisoprene/natural rubber composites
Four kinds of liquid polyisoprene (LIR) with different mole fraction of 3,4- unit were prepared, and the effects of aromatic oil and LIR with different mole fraction of 3,4- unit as plastici-zers on the cross-linking density, physical and mechanical ...
ZHANG Xiao-juana; b; YAN Zhi-xuana; b; SUN Chonga; LIU Lib; HE Li-xiab
doaj +1 more source
The aim of this study is to determine the radiographic position of the lateral intercondylar ridge (LIR) and its relationship with the Blumensaat line (BL) and the tangent to the posterior cortex (PCT) of the distal femur.
Leo Gulan +3 more
doaj +1 more source
Liraglutide abrogates nephrotoxic effects of chemotherapies
Acute kidney injury (AKI) is a common clinical complication. Cisplatin (Cis) is an effective chemotherapeutic drug; however, its acute nephrotoxicity often limits its application.
Cong Xu +9 more
doaj +1 more source
AlphaFold2-multimer guided high-accuracy prediction of typical and atypical ATG8-binding motifs
Macroautophagy/autophagy is an intracellular degradation process central to cellular homeostasis and defense against pathogens in eukaryotic cells. Regulation of autophagy relies on hierarchical binding of autophagy cargo receptors and adaptors to ATG8 ...
Tarhan Ibrahim +5 more
doaj +2 more sources
The characterization of suspended dust near the Martian surface is extremely relevant to understand the climate of Mars. In this frame, a Dust Sensor instrument, an infrared device designed to obtain the effective parameters of Martian dust using the ...
David Santalices +6 more
doaj +1 more source

