Results 11 to 20 of about 158,165 (242)

AlphaFold2-multimer guided high-accuracy prediction of typical and atypical ATG8-binding motifs

PLoS Biology, 2023
Macroautophagy/autophagy is an intracellular degradation process central to cellular homeostasis and defense against pathogens in eukaryotic cells. Regulation of autophagy relies on hierarchical binding of autophagy cargo receptors and adaptors to ATG8 ...
Tarhan Ibrahim, Virendrasinh Khandare, Federico Gabriel Mirkin, Yasin Tumtas, Doryen Bubeck, Tolga O. Bozkurt   +5 more
doaj   +2 more sources

Atg8 family proteins, LIR/AIM motifs and other interaction modes

Autophagy Reports, 2023
The Atg8 family of ubiquitin-like proteins play pivotal roles in autophagy and other processes involving vesicle fusion and transport where the lysosome/vacuole is the end station. Nuclear roles of Atg8 proteins are also emerging.
Vladimir V. Rogov, Ioannis P. Nezis, Panagiotis Tsapras, Hong Zhang, Yasin Dagdas, Nobuo N. Noda, Hitoshi Nakatogawa, Martina Wirth, Stephane Mouilleron, David G. McEwan, Christian Behrends, Vojo Deretic, Zvulun Elazar, Sharon A. Tooze, Ivan Dikic, Trond Lamark, Terje Johansen   +16 more
doaj   +1 more source

Calibration of a Dust Scattering Instrument Using Tomographic Techniques and Its Application to a Dust Sensor Instrument

Sensors, 2023
The characterization of suspended dust near the Martian surface is extremely relevant to understand the climate of Mars. In this frame, a Dust Sensor instrument, an infrared device designed to obtain the effective parameters of Martian dust using the ...
David Santalices, Mateo Martínez-García, Jesús Belmar, Daniel Benito, Susana Briz, Juan Meléndez, Antonio J. de Castro   +6 more
doaj   +1 more source

Ameliorative Impact of Liraglutide on Chronic Intermittent Hypoxia-Induced Atrial Remodeling

Journal of Immunology Research, 2022
Atrial fibrillation (AF) is the most frequent form of clinical cardiac arrhythmias. Previous evidence proved that atrial anatomical remodeling (AAR) and atrial electrical remodeling (AER) are crucial for the progression and maintenance of AF.
Jun Wang, Yongzheng Liu, Changhui Ma, Yue Zhang, Meng Yuan, Guangping Li   +5 more
doaj   +1 more source

The infrared compactness-temperature relation for quiescent and starburst galaxies [PDF]

, 2006
IRAS observations show the existence of a correlation between the infrared luminosity Lir and dust temperature Td in star-forming galaxies, in which larger Lir leads to higher dust temperature.
Alton, Alton, B. Guiderdoni, Becker, Bell, Bendo, Bendo, Blain, Cesarsky, Chapman, Chapman, Chapman, Chini, Chini, Condon, Condon, Condon, Condon, D. Elbaz, Dale, Dale, Dale, Dale, de Grijp, Devereux, Djorgovski, Dressler, Dumke, Dunne, Dunne, Désert, Eales, Engargiola, F. Hammer, H. Flores, Helou, Hildebrand, Hughes, Hunt, Jarrett, Karachentsev, Kennicutt, Kennicutt, Klaas, L. Vigroux, Lehnert, Lemke, Lonsdale-Persson, Meurer, Neugebauer, P. Chanial, Phillipps, Rice, Roussel, Rowan-Robinson, Sanders, Sanders, Sanders, Saunders, Schmidt, Serjeant, Smith, Soifer, Soifer, Soifer, Stark, Stevens, Stickel, Tonry, Toomre, Tuffs, Tully, Vlahakis, Véron-Cetty, Wang, Wilson, Young, Yun   +77 more
core   +3 more sources

On the implementation of LIR: the case of simple linear regression with interval data [PDF]

, 2012
This paper considers the problem of simple linear regression with interval-censored data. That is, n pairs of intervals are observed instead of the n pairs of precise values for the two variables (dependent and independent).
Cattaneo, Marco E. G. V., Wiencierz, Andrea   +1 more
core   +1 more source

Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?

Molecular & Cellular Oncology, 2017
Amplification of the candidate oncogene TLOC1/SEC62 in tumors correlates with reduced patient survival. The recently reported role of SEC62 as an autophagy receptor that controls endoplasmic reticulum (ER) size and function might open new scenarios for ...
Timothy J. Bergmann, Fiorenza Fumagalli, Marisa Loi, Maurizio Molinari   +3 more
doaj   +1 more source

Preparation of Lir@BSA-PMF nanoparticles and verification of their cell functions [PDF]

Jichu yixue yu linchuang
Objective To synthesize bovine serum albumin(BSA)-loaded liraqlutide (Lir)-nanoparticles coated with platelet membrane fragments (PMF) using a“bottom-up” nano-engineering chemistry technique, and to evaluate their cyto-compatibility and potential ...
HUANG Qingyu, CHEN Qiying, SUN Shengjia, WU Bangwei, LIN Shan, Alimujiang·MAIMAITIJIANG
doaj   +1 more source

The star formation rate cookbook at 1 < z < 3: Extinction-corrected relations for UV & [OII]{\lambda}3727 luminosities [PDF]

, 2015
We use a spectroscopic sample of 286 star-forming galaxies (SFGs) at ...
Cimatti, A., Daddi, E., Gruppioni, C., Kurk, J., Maraston, C., Mignoli, M., Pozzetti, L., Pozzi, F., Rodighiero, G., Talia, M.   +9 more
core   +4 more sources

Notch signaling is involved in the antiapoptotic effects of liraglutide on rat H9c2 cardiomyocytes exposed to hypoxia followed by reoxygenation

Journal of International Medical Research, 2020
Objective Liraglutide (Lir) protects cardiomyocytes against high glucose-induced myocardial damage. This study investigated whether Notch signaling participated in the antiapoptotic effects of Lir on rat H9c2 cardiomyocytes subjected to hypoxia followed ...
Juan Wu, Fei Xie, Yali Qin, Jie Liu, Zihua Yang   +4 more
doaj   +1 more source