Liraglutide prevents lupus-associated diffuse alveolar hemorrhage via inhibiting lymphocyte infiltration and promoting macrophage M2 polarization. [PDF]
Jiang L +6 more
europepmc +1 more source
Analysis of Obesity Care in Spanish Healthcare Settings: OBEQUIDAD Study
ABSTRACT Background Obesity management remains influenced by misconceptions about the disease, which compromise care quality. Introduction The OBEQUIDAD study explores the clinical management of people with obesity in Spain based on the perspectives of healthcare professionals involved in its treatment across different medical specialties.
Ana de Hollanda +7 more
wiley +1 more source
ABSTRACT Background GLP‐1 RAs are effective in treating obesity; however, they typically result in significant loss of skeletal muscle mass. Real‐world evidence to inform systematic guidelines and clinical implementation for preserving skeletal muscle mass and reducing cardiometabolic risk with lifestyle modifications on GLP‐1 RAs remains limited ...
Elizabeth Sharp Edens +3 more
wiley +1 more source
GLP-1 receptor agonists for weight loss: A systematic review and meta-analysis of randomized controlled trials. [PDF]
Ahmad N +6 more
europepmc +1 more source
Targeting Multiple Gut‐Brain Pathways in Obesity: Rationale for Combination Pharmacotherapy
ABSTRACT Background As a disease of energy dysregulation, obesity involves metabolic, hormonal, and neural factors, the interconnection of which is referred to as the “gut‐brain axis.” Objective This review aimed to provide an overview of the clinical evidence of physiological and objective or subjective changes in eating behavior with gut hormone ...
Alexander D. Miras, Muzamil Hussain
wiley +1 more source
Comparative evaluation of liraglutide plus metformin combination therapy versus metformin monotherapy in patients with type 2 diabetes mellitus: A retrospective clinical study. [PDF]
Mai T.
europepmc +1 more source
SGLT2 inhibitors reduce skeletal muscle mass modestly in older adults with type 2 diabetes. Forest plot (a) and count our funnel plot (b) show a small but significant pooled reduction in muscle mass (SMD = −0.36, 95% CI [−0.56, −0.15]; I2 = 24.1%), with weight loss occurring predominantly through fat mass reduction.
Weena Joongpan +5 more
wiley +1 more source
Incretin Analogues for Weight Reduction in Non-Diabetic Obese: A Review of Liraglutide, Semaglutide, and Tirzepatide Beyond Glycemic Control. [PDF]
Bonga KN, Padhan M.
europepmc +1 more source
ABSTRACT Obesity and T2DM substantially increase postoperative risk, with higher surgical site infections in obesity and up to a 65% increase in overall complications in T2DM. This study assesses the impact of weight loss interventions—metabolic bariatric surgery (MBS) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RA)—on BMI reduction and how ...
Shahzaib Zindani +10 more
wiley +1 more source
Liraglutide Ameliorates Injury-Related Vascular Repair by Activating Autophagy Through Modulation of the PI3K-mTOR Signaling Pathway. [PDF]
Zhang Z +14 more
europepmc +1 more source

