Differences in the Effectiveness of Uridine and Liriope platyphylla L. Between Complement Component 3 Deficiency- and Loperamide-Induced Constipation May Be Associated with the Alternative Regulation of the Cyclic Adenosine Monophosphate Downstream Signaling Pathway [PDF]
PharmaceuticalsBackground/Objectives: Constipation can be induced in animal models through various factors such as loperamide (Lop) or complement component 3 (C3) deficiency.
Hee Jin Song +11 more
doaj +2 more sources
Anti-Inflammatory Effects of the LK5 Herbal Complex on LPS- and IL-4/IL-13-Stimulated HaCaT Cells and a DNCB-Induced Animal Model of Atopic Dermatitis in BALB/c Mice [PDF]
Pharmaceutics, 2023 Atopic dermatitis (AD) is a chronic inflammatory skin disease influenced by a complex interplay of genetic and environmental factors. The activation of the JAK-STAT pathway increases the expression of inflammatory cytokines such as IL-4 and IL-13 ...
Hyun-Jeong Kim +12 more
doaj +2 more sources
Characterization of Changes in Global Genes Expression in the Distal Colon of Loperamide-Induced Constipation SD Rats in Response to the Laxative Effects of Liriope platyphylla. [PDF]
PLoS ONE, 2015 To characterize the changes in global gene expression in the distal colon of constipated SD rats in response to the laxative effects of aqueous extracts of Liriope platyphylla (AEtLP), including isoflavone, saponin, oligosaccharide, succinic acid and ...
Ji Eun Kim +9 more
doaj +2 more sources
Effect of Spicatoside a on Anti-Osteosarcoma MG63 Cells through Reactive Oxygen Species Generation and the Inhibition of the PI3K-AKT-mTOR Pathway [PDF]
AntioxidantsOsteosarcoma is a primary malignant tumor found in the bones of children and adolescents. Unfortunately, many patients do not respond well to treatment and succumb to the illness.
Hyung-Mun Yun +3 more
doaj +2 more sources
Immunomodulatory effects of Liriope platyphylla water extract on lipopolysaccharide-activated mouse macrophage. [PDF]
Nutrients, 2012 The tuber of Liriope platyphylla Wang et Tang (Liliaceae), also known as Liriopis tuber, is famous in Oriental medicine owing to its tonic, antitussive, expectorant and anti-asthmatic properties. In the present study, the effects of Liriopis tuber water extract (LP) on proinflammatory mediators secreted from lipopolysaccharide (LPS)-induced cultured ...
Kim HK +10 more
europepmc +5 more sources
Efficacy of liriope platyphylla extract for improving respiratory functions: Study protocol for a randomized, double-blinded, placebo-controlled pilot trial. [PDF]
Medicine (Baltimore), 2022 Abstract Background: Respiratory disease has emerged as a global issue due to COVID-19. In particular, there has been an increased frequency of occurrence of symptoms such as cough, sputum, and dyspnea, which commonly accompany chronic obstructive pulmonary disease (COPD).
Jung GH, Park CH, Lee H, Kang JH.
europepmc +3 more sources
Active Constituents from Liriope platyphylla Root against Cancer Growth In Vitro. [PDF]
Evid Based Complement Alternat Med, 2013 Liriope spicatais a well-known herb in traditional Chinese medicine, and its root has been clinically demonstrated to be effective in the treatment of metabolic and neural disorders. The constituents isolated fromLiriopehave also recently been shown to possess anticancer activity, although the mechanism of which remains largely unknown.
Wang HC +8 more
europepmc +4 more sources
Current Plant Biology, 2022 Liriope platyphylla F.T. Wang & Tang and Ophiopogon japonicus (Thunb.) Ker Gawl are morphologically similar perennial herbaceous plants belonging to the Asparagaceae family used as evergreen ornamental plants as well as for medicinal purposes ...
Yeonjeong Lee +8 more
doaj +1 more source
Food Science &Nutrition, Volume 11, Issue 9, Page 5028-5040, September 2023., 2023 A broad range of functional food components with antioxidant and/or anti‐inflammatory properties have been explored that can induce detoxification effects against ethanol. The underlying mechanisms of these bioactive food components include reducing the intestinal absorption of ethanol or its metabolites, increasing the activity of ethanol metabolizing
Masoumeh Moslemi +4 more
wiley +1 more source
Commodity risk assessment of Fagus sylvatica plants from the UK
EFSA Journal, Volume 21, Issue 7, July 2023., 2023 Abstract The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’. This Scientific Opinion covers plant health risks posed by plants of Fagus sylvatica imported from the ...
EFSA Panel on Plant Health (PLH) +30 more
wiley +1 more source