Results 81 to 90 of about 115,985 (312)
Discrete Applied Mathematics, 1993 Given a set \(T\) and an integer \(k\), a graph \(G\) is \(T-k\) choosable if, for every assignment of (possibly different) lists of \(k\) integers to the vertices of \(G\), there exists a \(T\)-colouring of \(G\) colouring each vertex with an element from the list assigned to that vertex.
openaire +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
BROOKS’ THEOREM FOR MEASURABLE COLORINGS
Forum of Mathematics, Sigma, 2016 We generalize Brooks’ theorem to show that if $G$ is a Borel graph on a standard Borel space $
CLINTON T. CONLEY +2 more
doaj +1 more source
List Edge Colorings of Planar Graphs without Adjacent 7-Cycles [PDF]
, 2021 Wenwen Zhang
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Fractional (P,Q)-Total List Colorings of Graphs
Discussiones Mathematicae Graph Theory, 2013 Let r, s ∈ N, r ≥ s, and P and Q be two additive and hereditary graph properties. A (P,Q)-total (r, s)-coloring of a graph G = (V,E) is a coloring of the vertices and edges of G by s-element subsets of Zr such that for each color i, 0 ≤ i ≤ r − 1, the ...
Kemnitz Arnfried +2 more
doaj +1 more source