Results 101 to 110 of about 106,069 (251)

Discovery and Communication of Important Marketing Findings: Evidence and Proposals [PDF]

open access: yes, 2002
My review of empirical research on scientific publication led to the following conclusions. Three criteria are useful for identifying whether findings are important: replication, validity, and usefulness.
Armstrong, J. Scott
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Evolution of social norms with heterogeneous preferences: A general model and an application to the academic review process [PDF]

open access: yes
The article presents a model of social norm evolution, which suggests how the increase in optimal and actual first response times (FRT) of economics journals can be related.
Azar, Ofer H.
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Recruiting and Integrating Personnel in a Sporting Organization. Case Study: Liga Economistului, 2010-2011 Season [PDF]

open access: yes
The paper presents how the recruitment and integration process of personnel was managed in Liga Economistului, a football championship in college sport. Sporting organizations, like for example leagues, clubs, associations, federations or teams, may find
Vlad ROSCA
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Acknowledgements for reviewers 2015-2016

open access: yesMaderas: Ciencia y Tecnología, 2016
The Scientific-Editor and Technical-Editor of Maderas-Cienc Tecnol are grateful to the reviewers for their assistance as referees into the peer review processes of the journal.The quality of the scientific contents of the Maderas-Cienc Tecnol depends on ...
Maderas-Cienc Tecnol
doaj  

Is Review By Peers As Fair As It Appears? [PDF]

open access: yes
Recent research shows that journal reviewing practices are neither objective nor fair. I propose a procedure to increase the likelihood of publishing important papers.
JS Armstrong
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

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