Results 91 to 100 of about 1,585,343 (306)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

THEMATIC PROGRESSION AND ITS TYPES IN ENGLISH LITERARY AND LEGISLATIVE TEXTS

open access: yesNovìtnâ Osvìta, 2019
The focus of the article is Thematic Progression as a text and a genre forming phenomenon. Thematic Progression contributes to  the cohesive development of any text, the distribution of given and new information of which needs to follow certain patterns.
Marina Kizil, Elina Kushch
doaj   +1 more source

Entrepreneurial Literary Theory: A Debate on Research and the Future of Academia [PDF]

open access: yes, 2017
Across the world at present, researchers and teachers are being exhorted to become entrepreneurial. Universities are being restructured accordingly. The debate presented in this book considers what that involves and portends for academia.
Durao, Fabio A.   +3 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Petit état de la théorie littéraire contemporaine

open access: yesSillages Critiques, 2000
This article concerns questions of rhetoricity and doxa in contemporary literary theory.
Jean Bessière
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Tropical Gothic and Beyond: El Grupo de Cali’s Legacies for Contemporary Latin American Literature, Cinema, and Culture

open access: yeseTropic: electronic journal of studies in the tropics, 2019
The creation and development of a tropical gothic is arguably the most important legacy of El Grupo de Cali, an interdisciplinary collective led by writer and film critic Andrés Caicedo Estela, and filmmakers Carlos Mayolo and Luis Ospina, during the ...
Felipe Gómez G.
doaj   +1 more source

The Literary Field in California: A Report to the James Irvine Foundation: Executive Summary [PDF]

open access: yes, 1999
Provides a scan of the nonprofit literary field in California, with an emphasis on literary presenters and writers.

core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Preoccupations of Some Asian Australian Women’s Fiction at the Turn of the Twenty-first Century

open access: yeseTropic: electronic journal of studies in the tropics, 2017
This paper offers a look back over the rise of the visibility, and the rise as a category, of Asian Australian fiction from the beginning of the 1990s, and especially in the twenty-first century, and some of the main questions that have been asked of it ...
Carole Ferrier
doaj   +1 more source

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