Results 101 to 110 of about 1,585,343 (306)

Writing for their lives: women applicants to The Royal Literary Fund [PDF]

open access: yes, 1990
The purpose of this article is to fill some of the gaps in our knowledge of those women writers in the lower echelons of the literary world of mid-Victorian England.
Mumm, S.D.
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Cultural ecology and Chinese Hamlets [PDF]

open access: yes, 2011
This essay examines the critical potential of cultural ecology and cultural mobility studies for modeling the relations between literature and culture. It investigates the mobility and portability of literary effects across different media, periods, and ...
Berensmeyer, Ingo
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Comparing Literary and Non-literary Texts Through Critical Reading Approach on Reading Comprehension [PDF]

open access: yes, 2015
Penelitian ini bertujuan untuk (1) menginvestigasi apakah ada perbedaan pemahaman siswa yang diajar menggunakan teks literary dan non-literary melalui pendekatan membaca critis. (2) menemukan teks manakah yang paling effektif untuk memahami bacaan. Untuk
Nurrohmah, I. (Irmaya)   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

LIFE AND LITERARY WORK OF IVAN DEŽMAN

open access: yesFluminensia: Journal for Philological Research, 1995
Ivan Dežman is a Croatian writer who wrote a considerable amount of literary and medical works. At one time he was considered a very outstanding writer, physician and intellectual, but his work was later evaluated differently.
Milorad Stojević
doaj  

A Questioning Agent for Literary Discussion [PDF]

open access: yes, 2019
Developing a compelling and cohesive thesis for analytical writing can be a daunting task, even for those who have produced many written works, and finding others to engage with in literary discussion can be equally challenging.
Culkin, Robbie, Shur, Tim
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

E-Legitimate Offspring: Tracing Literary and Ludic Convergence

open access: yesHumanities
We can trace the convergence of electronic literature and narrative games through a focus on critical methods and experiential frameworks rather than relying on typologies or ontologies.
David Ciccoricco
doaj   +1 more source

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