Results 71 to 80 of about 424,468 (290)

APPLYING LITERARY ETHICAL CRITICISM TO TEACHING READING COMPREHENSION OF LITERARY TEXTS TOWARDS THE GOAL OF DEVELOPING STUDENTS' QUALITIES ACCORDING TO THE 2018 GENERAL EDUCATION PROGRAM

open access: yesTạp chí Khoa học
The article begins by applying moral literary criticism in teaching literary text comprehension and provides an overview of the theory of ethical literary criticism.
Do Thi Thuy Duong
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

New Perceptions: Kinugasa Teinosuke\u27s Films And Japanese Modernism [PDF]

open access: yes, 2004
This essay offers a reading of Kinugasa Teinosuke\u27s independent silent films as responses to the traumatic experience of twentieth-century modernity. Of particular interest are the global and local intertexts in A Page of Madness and Crossways, their ...
Gardner, William O.
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Hispamérica and literary criticism

open access: yesEstudios de Teoría Literaria, 2018
The article studies the various modalities that the Hispamérica journal has taken in relation to Latin American literary criticism during the first two decades of its publication, between the 70s and the 80s.
Roxana Patiño
doaj  

To Be or Not To Be (a Man): Is That the Question? Men and/in Feminist Literary Criticism [PDF]

open access: yes, 2008
[Abstract] While the question of men and/in feminism has long been subject to different (and often opposed) views and opinions, the more specific issue of men in feminist literary criticism remains largely unexplored. Nevertheless, the question of men in
Armengol, Josep M.
core  

Al hilo de la literatura latinoamericana : estudios literarios/estudios culturales / To the thread of Latin American literature: literary studies / cultural studies [PDF]

open access: yes, 2017
The present work constitutes a bibliographical route by the criticism and the Hispano-American literary theory of the last 50 years. Its author did not pretendan exhaustiveness, but a collective task of congresses etc. Its most significant milestones are:
Caballero Wangüemert, María
core   +3 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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