Results 71 to 80 of about 48,547 (300)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Literary Criticism after Literature

open access: yes, 2020
The article is focused on literary criticism within the post-literary formation. The author describes it in the historical and cultural perspective of institutional changes and the consequences of different ways of defining literature and its functions ...
Uniłowski, Krzysztof
core   +1 more source

Literary Criticism in the Ottoman-Turkish Literature: From Tanzimat to Republican Period / OSMANLI-TÜRK EDEBİYATI TARİH YAZIMINDA TANZİMAT’TAN BUGÜNE ÇAĞDAŞ ELEŞTİREL SÖYLEM [PDF]

open access: yesFolklor/Edebiyat, 2016
Literary criticism has always been based on the literary realm as well as the political realm since the Tanzimat period. The first feature of the literary criticism in the OttomanTurkish literature is the transformation of itself into a symbol of ...
Şeyda Başlı *
doaj  

Meta-composition and literary criticism on the Persius’ first satire

open access: yesCadernos de Letras da UFF, 2018
The comic traces that lead to questionings and criticism had always been part of the Roman soul. Nevertheless, literary criticism would be enforced only within the genres born from the Hellenistic influence that was growing since the fall of the Republic.
Lucas Amaya
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Representing the economy and the economies of representation : readings in the fiction and criticism of Henry James [PDF]

open access: yes
This thesis is structured around exchanges between contemporary critical theory and the fiction, criticism and context of Henry James. In Chapter 1 I discuss readings of James and theories of reading as an active process.
Webster, Duncan
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Hispamérica and literary criticism

open access: yesEstudios de Teoría Literaria, 2018
The article studies the various modalities that the Hispamérica journal has taken in relation to Latin American literary criticism during the first two decades of its publication, between the 70s and the 80s.
Roxana Patiño
doaj  

Home - About - Disclaimer - Privacy