Results 41 to 50 of about 6,195 (254)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Meta-composition and literary criticism on the Persius’ first satire
Cadernos de Letras da UFF, 2018 The comic traces that lead to questionings and criticism had always been part of the Roman soul. Nevertheless, literary criticism would be enforced only within the genres born from the Hellenistic influence that was growing since the fall of the Republic.
Lucas Amaya
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Rediscovering Horror – From Graveyard Poetry to Popular Culture
[sic], 2016 Horror: A Literary History, edited by Xavier Aldana Reyes, is divided into seven chapters which function as separate essays that can be read without having specific knowledge about the horror genre.
Emilia Musap
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Publishing and Literary System in Basque Literature
Rassegna Iberistica, 2015 The article outlines the creation of the Basque literary system, the relations of mediation between publishers and readers of literature written in Basque, through its evolution during the 20th Century. Being the Basque literary system of a precarious
Kortazar, Jon
doaj +1 more source
Norwegian Innvandrerlitteratur and the Spell of Transnationalism
Metacritic Journal for Comparative Studies and Theory, 2017 This paper focuses on the current evolution of Norwegian literature, namely on the branch of Norwegian literary activity that falls within the theoretical frame of ‘immigrationist literature’ (innvandrerlitteratur).
Ovio Olaru
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source