Results 61 to 70 of about 6,195 (254)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
MoussonsIn a society undergoing profound transformation after the establishment of colonial rule, a new literature emerged in Vietnam, with new literary genres including the novel.
Nguyễn Giáng Hương
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The Early Literary Evolution of the Notorious Pirate Henry Avery
Humanities, 2019 Henry Avery (alternately spelled Every) was one of the most notorious pirates of the late seventeenth and early eighteenth centuries, and scholars have written much about Avery in an effort to establish the historical details of his mutiny and acts of ...
Richard Frohock
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Russian literary museums: genesis and evolution [PDF]
Vestnik of Saint Petersburg State University of Culture, 2017 The retrospective analysis of the museums and ways of its evolutionary formation has allowed to define time of its origin and to allocate four periods in history of their development as cultural institution. Approaches to a solution of the problem of correlation between original and typological in a literary exposition are revealed. The literary museum
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Cette aveuglante absence de lumière
Francosphères, 2016 Drawing on Samia Mehrez’s work on the subversive use of French by Maghrebi writers and Pascale Casanova’s theory on literary dissemination, this article examines the politics of literary production in foreign languages and the exposure of human rights ...
Brahim El Guabli
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Orbis Tertius, 2005 The article remembers the attempts of systematization of knowledge previous to the Romanticism and summarizes the evolution of the literary historiography during centuries XIX and XX to later present/display some methodological reflections with respect ...
Christian Wentzlaff-Eggebert
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