Results 31 to 40 of about 17,389 (269)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Deseo y autoridad: la tensión de la autoría en María de Zayas
Criticón, 2017 Zayas organizes a double and specular series of novels inserted in an atmosphere of a charming evening party, together with a love affair. Frame story and each story within that frame present different situations and stories about the love theme.
Emre Özmen, Pedro Ruiz Pérez
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
QUE LES PERDONEN LA VIDA: AUTOBIOGRAFÍA Y MEMORIAS EN EL CAMPO LITERARIO CHILENO
Revista Chilena de Literatura, 2011 Si bien en Chile existen textos de carácter autobiográfico desde la época colonial, hasta muy entrado el siglo XX estos apenas ocupan un lugar en la conformación del campo literario nacional, ya que son excluidos por críticos e historiadores de sus ...
Lorena Amaro Castro
doaj
An Outline of the Changes in Slovak Literary Criticism from the Mid-1960s to the Early 1970s. (3th Part) [PDF]
Slovenska Literatura, 2015 This literary history paper is concerned with the changes of Slovak literary criticism over a certain period of time. It reconstructs the process of the criticism becoming temporarily emancipated, i.e.
Vladimír Barborík
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Imaginations: Journal of Cross-Cultural Media Studies, 2021 The Frankfurt Book Fair is the world’s largest literature and media event. Every year the book fair offers an internationally recognized platform to a guest country in order to present its literature and culture.
Helmi-Nelli. Körkkö
doaj
Social Status and Reputation of Writers in Modern Russia: Thematic Analysis
Интеракция. Интервью. Интерпретация, 2023 This article examines the forms of social evaluation of writers' work in modern Russia. As a methodological basis, the theory of the “literary field” developed by Pierre Bourdieu and his followers is used, on the basis of which a conceptual and empirical
Alexander Pavlovich Ryazancev
doaj +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source