Results 51 to 60 of about 17,786 (267)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Being an Author: Literary Identities of Work in the Contemporary German Literary Field

open access: yesSwiss Journal of Sociology, 2017
This article considers the normative conceptions and images that contemporary German fiction authors associate with their own work. On the basis of twenty narrative interviews, the article examines the extent to which the different self-reflections of ...
Amlinger Carolin
doaj   +1 more source

La littérature en dispositif de politique publique. Les résidences d’écrivains franciliennes entre création et territoires

open access: yesCulture & Musées, 2018
Analysing the case of writing residencies proposed in 2017 in Paris’ area, using some interviews conducted with writers and representants of political and literary institutions, and some posts published on the web by authors, mediators and publics, this ...
Cécile Rabot
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Literary tourism as a field of research over the period 1997-2016

open access: yesEuropean Journal of Tourism Research, 2020
Although literary tourism is not a new concept, the academic research in this field has not been able to reach adequate level since it has not come to the forefront yet as a tourism type in many parts of the world.
Samet Çevik
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

De bachilleres y graduados: Alonso de Castillo Solórzano y la novela académica en el contexto del campo literario

open access: yesCriticón, 2019
The work of Castillo Solórzano, an author who emerged within the context of the academies, is marked by the influence of this eminent institution of the Spanish Golden Age culture in such a way that much of his novelistic production is related to in the ...
Mechthild Albert
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Crossing the Magical Barriers of Art: Social Class, Authorship and Capital in the Contemporary Finnish Literary Field

open access: yesNordisk Kulturpolitisk Tidsskrift, 2019
This article examines how social class origin is experienced to affect the trajectories of becoming and being an author in the context of the contemporary Finnish literary field.
Taija Roiha
doaj   +1 more source

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