Results 61 to 70 of about 632,201 (233)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Introduction to Forum: The Hemispheric French Atlantic [PDF]

open access: yes, 2015
“The Hemispheric French Atlantic” begins to suture a transatlantic to a hemispheric spatiality by tracing out the movement of texts, figures, and traditions within a complex and kinetic circulatory system that moves beyond the geometric model imagined by
Burnham, Michelle
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

QUE LES PERDONEN LA VIDA: AUTOBIOGRAFÍA Y MEMORIAS EN EL CAMPO LITERARIO CHILENO

open access: yesRevista Chilena de Literatura, 2011
Si bien en Chile existen textos de carácter autobiográfico desde la época colonial, hasta muy entrado el siglo XX estos apenas ocupan un lugar en la conformación del campo literario nacional, ya que son excluidos por críticos e historiadores de sus ...
Lorena Amaro Castro
doaj  

Coronas del Parnaso y Platos de las musas de Alonso Jerónimo de Salas Barbadillo

open access: yesMélanges de la Casa de Velázquez, 2013
This article proposes a study of the dedications in Coronas del Parnaso y Platos de las musas by Alonso Jerónimo de Salas Barbadillo (Madrid, 1635), to show how the miscellany, the variety of forms and the hybrid nature of this curious work reflect an ...
Anne Cayuela
doaj   +1 more source

Crossovers: Digitalization and literature in foreign language education [PDF]

open access: yes, 2019
Digitalization produces increasingly multimodal and interactive literary forms. A major challenge for foreign language education in adopting such forms lies in deconstructing discursive borders between literary education and digital education (romance of
Lütge, Christiane   +3 more
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Being an Author: Literary Identities of Work in the Contemporary German Literary Field

open access: yesSwiss Journal of Sociology, 2017
This article considers the normative conceptions and images that contemporary German fiction authors associate with their own work. On the basis of twenty narrative interviews, the article examines the extent to which the different self-reflections of ...
Amlinger Carolin
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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