Results 101 to 110 of about 597,924 (360)
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Primary school, science, and scientific literary [PDF]
Education can be imagined as a series of human experiences that supplement and reinforce each other to provide the depth and breadth of knowledge that are necessary to deal with, and contribute to, the details of living in a technological society. Primary school is a key component in the development of a modern, technologically-based society, so why is
openaire +1 more source
L'article és una revisió de les opinions de diversos autors sobre l'estil dels científics en escriure ciència.This article is a review of opinions of different authors about literary style of scientists writing ...
Domínguez, Martí
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Reviews of Dead Sea Scrolls and the Bible, by James Vanderkam. Grand Rapids: William B. Eerdmans, 2012. 188 pp. $17.00; ISBN 0-8028-6679-0. Reviewed by Robert Burgess, Head, Acquisitions, Midwestern Baptist Theological Seminary, Kansas City, Missouri ...
Fox, Phyllis
core +31 more sources
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
The Original Sin of Writing and Reading
This study examines the possible points of connection between crime and reading on the basis of genre-typical roles and motifs in detective fiction. I aim to identify characteristic reading methods, strategies, locations, events, and professions with ...
Kristián Benyovszky
doaj +1 more source

