Results 81 to 90 of about 32,579,599 (302)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Florence Hayes Literary Club, yearbook, 1942-1943

open access: yes, 2020
The Florence Hayes Literary Club was a private club dedicated to women's education. This yearbook contains information on officers, meeting schedules and agendas, committee membership lists, and a membership ...
Florence Hayes Literary Club (Toledo, Ohio)
core  

Neural machine translation of literary texts from English to Slovene

open access: yes, 2019
Neural Machine Translation has shown promising performance in literary texts. Since literary machine translation has not yet been researched for the English-toSlovene translation direction, this paper aims to fulfill this gap by presenting a comparison ...
Kuzman, Taja   +2 more
core   +1 more source

From Readers to Data. Uncertainty in Computational Literary Citizen Science

open access: yesJournal of Computational Literary Studies
We examine uncertainty in computational literary citizen science by analysing The Hebrew Novel Project, a large-scale initiative collecting reader interpretations of Hebrew novels.
Gilad Aviel Jacobson   +2 more
doaj   +2 more sources

Mediascape’s Drifter

open access: yesOpen Cultural Studies, 2018
Today, mediascapes (see Appadurai) play a predominant role in the construction of modes of human existence. How do they determine our agency? How do they form screens for our emotions, how do they build non-negligible spaces in which our dramas play out?
Zaleski Marek
doaj   +1 more source

Social Science and Literary Criticism: What is at stake?

open access: yesHTS Teologiese Studies/Theological Studies, 1993
As the variety of methods used by biblical scholars multiplies, new sub-disciplines are being born that all too often leave specialists isolated from each other.
R. L. Rohrbaugh
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Florence Hayes Literary Club, yearbook, 1947-1948

open access: yes, 2020
The Florence Hayes Literary Club was a private club dedicated to women's education. This yearbook contains information on officers, meeting schedules and agendas, committee membership lists, and a membership ...
Florence Hayes Literary Club (Toledo, Ohio)
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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