Results 61 to 70 of about 46,893 (290)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

From Bion to Delany

open access: yesLanguage and Psychoanalysis, 2020
Literature furnishes a particular vertex to see reality through narrative fiction. In particular, science fiction literature, which creates a fantastic situation starting from realistic data (history, science, cultures), may be considered a kind of ...
Riccardo Gramantieri
doaj   +1 more source

The Modality of the Textual Institutionalisation of Literary Studies: Towards a Sociology of Literature [PDF]

open access: yes
This paper aims to present a sociology of literary studies that is distinguished from the sociology of literature in that its focus is on literary studies as a social practice rather than as a socio-cultural institution: how literary studies is ...
Soh-young Chung
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The literary science of the 'Kafkaesque'

open access: yes, 2009
This study provides a precise definition of the term 'Kafkaesque' by enriching literary criticism with scientific theory and practice, including an experiment on readers' responses to Kafka. Dictionary definitions justify taking the term back to its textual origins in Kafka's works, and the works can fruitfully be analysed by investigating how readers ...
openaire   +2 more sources

Literature of law: between legal science and literary criticism

open access: yesAnamorphosis, 2018
This work questions the relationship between law – rules, power, strength and legal security –  and literature – open, ductile, revulsive of “having to” and dreamy with what “should be”.
Leonor Suárez Llanos
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The literary arts in Hume's science of the fancy

open access: yesKriterion, 2003
Philosophers have long disagreed about whether poetry, drama, and other literary arts are important to philosophy; and among those who believe that they are important, explanations of that importance have differed greatly.
Don Garrett
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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