Results 31 to 40 of about 69,750 (309)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Invisible Authors, Visible Gender: How Readers Infer Author Gender from Fiction
Open Cultural StudiesThis article examines how gender shapes readers’ perceptions of literary authorship when biographical information is withheld. Using an explanatory mixed-methods design, it investigates how male and female university students infer an author’s gender ...
Mereke Zeinollakizi
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker +11 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
The History of the Spanish Preposition Mediante. Beyond the Theory of Grammaticalization
Languages, 2019 The most generally accepted diachrony of mediante assumes a grammaticalization path that started in an absolute clause, which first evolved into a preposition, and later into conjunction.
Mar Garachana
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
, 2022 The article proposes a conversation on Cognitive Literary Studies with Marco Caracciolo, Monika Fludernik, Patrick Colm Hogan and Karin Kukkonen. Starting from a methodological reflection on the interdisciplinarity of this field, the scholars were asked ...
Mutti, Chiaraeditor +1 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
PARALLELED CHARACTERS IN THE DRAMATIC WORKS OF HORTENSIA PAPADAT-BENGESCU [PDF]
Diversitate si Identitate Culturala in Europa, 2015 This article proposes a psychoanalytical approach to two paralleled literary characters whom Hortensia Papadat-Bengescu places into opposition in order to introduce her readers to feminine hypostases of wish fulfilment.
Simona GALAŢCHI
doaj