Results 51 to 60 of about 69,750 (309)
From Plato’s Republic and Aristotle’s Poetics onwards, tragedy has loomed large in the genealogy of literary theory. But this prominence is in many regards paradoxical.
Toscano, Alberto, Alberto Toscano
core +1 more source
Jacques Lacan (Pre-published version)
Jacques Marie Émile Lacan was born on April 13, 1901 and died on September 9 1981. He was a French psychoanalyst and philosopher and was a very controversial figure on the French psychoanalytic scene.
core +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
“The case” of Poor Ioanide, or on critical reception in different stages of post-war Romanian literary history [PDF]
This article aims to present some aspects regarding the critical reception of the novel Bietul Ioanide, whose subject is set in the post-war period.
Ana-Maria BĂNICĂ
doaj
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
THE VALUE OF RELEVANCE THEORY IN LITERARY ANALYSIS [PDF]
Artikel ini mengkaji pandangan Formalist Linguistics dan Relevance Theory terhadap karya sastra. Formalist Linguistics berpandangan bahwa nilai sebuah karya sastra terletak pada keistimewaan bahasanya.
Candria, Mytha
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The article analyzes the symptomatic representations of maternal experience in the modern Romanian novel written by women. It aims to draw attention to maternal voices portrayed in literary texts across national contexts at the beginning of the 20th ...
Ioana Moroșan
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source

