Results 61 to 70 of about 630,776 (307)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mediações Dilaceradas: Linguagem e Experiência no Pensamento de Theodor Adorno

open access: yesMatLit, 2013
This article focuses on the concept of "mediation" as used by Adorno throughout his philosophical and critical work. Starting with his discussion about culture in contemporary society, the paper examines his reflections on language as a process lacerated
Matheus de Brito
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Stimmungen or "In the Mood for Differentiality"

open access: yesMatLit, 2014
Review of Hans Ulrich GUMBRECHT. Atmosphere, Mood, Stimmung: On a Hidden Potential of Literature, Trans. Erik Butler, Stanford, CA: Stanford University Press, 2012, pp. 148 [1st ed. Munich, Carl Hanser Verlag, 2011].
Matheus de Brito
doaj   +1 more source

Partial Evidence: An enquiry concerning a possible affinity between literary moral cognitivism and moral pluralism [PDF]

open access: yes, 2017
This paper begins by affirming the view that if there is a debate to be had over whether literature can convey moral knowledge, then efforts by proponents to substantiate this claim will already be necessarily conditioned by an understanding of what ...
Shum, Peter
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

How Do We Read in the Age of Intertextual Digitalism?Bibliography and webography [PDF]

open access: yesDiversitate si Identitate Culturala in Europa
The study is a reflection about how reading practices, habits, attitudes and methods changed in the most recent context of digitalism. This type of digital globalization has many consequences on humanistic studies.
George NEAGOE
doaj  

The Persian Translation of Arabic Aesthetics: Rādūyānī’s Rhetorical Renaissance [PDF]

open access: yes, 2015
Notwithstanding its value as the earliest extant New Persian treatment of the art of rhetoric, Rādūyānī’s Interpreter of Rhetoric (Tarjumān al-Balāgha) has yet to be read from the vantage point of comparative poetics.
Gould, Rebecca Ruth
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Augustin Buzura’s Orgolii: on the “faces” of Romanian communism [PDF]

open access: yesDiversitate si Identitate Culturala in Europa
This study aims to demonstrate that Romanian novelists of the 1960s unveil both the terror of the Dej regime and the more sophisticated methods of torture employed under Ceaușescu.
Ana-Maria BĂNICĂ
doaj  

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