Results 201 to 210 of about 17,762,432 (299)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Mesenteric Hemolymphangioma: A Case Report and Literature Review. [PDF]

Am J Case Rep
Geng D, Tao J, Miao Y.
europepmc   +1 more source

State of the Art Literature Review on Network Anomaly Detection with Deep Learning

, 2018
Tero Bodström, Timo Hämäläinen
openalex   +2 more sources

Endometriosis-associated Maternal Pregnancy Complications – Case Report and Literature Review [PDF]

, 2016
J. Petresin, Jacqueline Wolf, Sümeyye Nur EMİR, Andreas Müller, Alexander Boosz   +4 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Corrigendum to "Author's response to Letter to the Editor re: Paz-Ilbarra C-ZM et al. A giant parathyroid cyst causing primary hyperparathyroidism in a pregnant woman: Case report and literature review". [PDF]

Obstet Med
europepmc   +1 more source

The burden of systemic therapy administration route in treating HER2-positive breast cancer (for patients, healthcare professionals, and healthcare system): a systematic literature review

Luciana Castro Garcia Landeiro, Tamie de Camargo Martins, Ruth Bartelli Grigolon, Isabel Monteiro, Joana Bisol Balardin, Eduardo Padilha, Gilberto Amorim, Stephen Stefani   +7 more
openalex   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

On the interpretation of preoperative HbA1c thresholds in minimally invasive lumbar surgery. [PDF]

Acta Neurochir (Wien)
Abudayeh A.
europepmc   +1 more source

Mathematical modeling of SCD: a literature review

Quindel Jones, Reginald L. McGee, Rebecca Segal, Wally R. Smith, Cecelia Valrie   +4 more
openalex   +1 more source