Results 71 to 80 of about 21,471,842 (381)
Material appearing below is thought to be of particular interest to Linacre Quarterly readers because of its moral, religious, or philosophic content. The medical literature constitutes the primary, but not the sole source of such material.
Catholic Physicians\u27 Guild
core +4 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Thoughts on the Literature Review and GT
Thinking about epistemic questions always reminds me of Socrates’ cave allegory. In Plato’s most famous book,The Republic, Socrates talks to a young follower named Glaucon.
Thoughts on the Literature Review and GT
doaj
Poetry, resistance, world-literature : Adília Lopes and Marie Buck [PDF]
This essay begins an exploration of how poetry functions within the field of world-literature, drawing specifically on the Warwick Research Collective’s Combined and Uneven Development: Towards a New Theory of World-Literature and reflecting ...
de Medeiros, Paulo
core +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Material appearing below is thought to be of particular interest to Linacre Quarterly readers because of its moral, religious, or philosophic content. The medical literature constitutes the primary but not the sole source of such material.
Catholic Physicians\u27 Guild
core +4 more sources
Youth gangs, sexual violence and sexual exploitation: a scoping exercise for the Office of the Children's Commissioner for England [PDF]
This report presents the findings of a scoping exercise on the issue of youth gangs, sexual violence and sexual exploitation, derived from key informant interviews and a literature ...
Pearce, Jenny J., Pitts, John
core
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source