Results 61 to 70 of about 36,289 (301)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

National Code in the Literature of Kazakhstan and Central Asia

Qubahan Academic Journal
The aim of this study is to explore how the “national code,” encompassing cultural values, historical memory, and identity, is represented in Kazakh and Central Asian literature through the lenses of classical narratology and distant reading.
Alibek Baibolov, Saule Abisheva, Akhlima Saparova, Zhanakul Sametova, Dina A. Sabirova, Yeldos Toktarbay   +5 more
doaj   +1 more source

Study of Literary Theory and Chinese Modern and Contemporary Literature

Journal of Higher Education Research, 2022
There is a close relationship between literary theory and contemporary Chinese literature, and the integration of knowledge from different disciplines. To realize the development of contemporary Chinese literature, not only the support of literary theory research is needed, but also the research results of different disciplines and the integration of ...
Yujie He, Yang Zou
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Arquivos e Edições Digitais

MatLit, 2013
Brief introduction to seven digital archives: Rossetti Archive, Dickinson Electronic Archives, The William Blake Archive, Radical Scatters, Arquivo Pessoa, Espólio Fernando Pessoa and Samuel Beckett Digital Manuscript Project.
Manuel Portela, Matheus de Brito
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Cinema e Literatura em Linha

MatLit, 2014
Brief presentation of eight online publications on cinema and literature: David Bordwell, Girish Shambu, Jonathan Rosenbaum, Film Studies for Free, La Furia Umana, Revista Cinética, Letraceluloide, Adaptaciones de la Literatura española.
Matheus de Brito, Osvaldo Manuel Silvestre   +1 more
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Notes for a notional-epistemic historiography of literature and literary theory. First issue: the "nature by philosophers"

Estudios de Teoría Literaria, 2023
In this paper we will try, based on the contributions of Juan Carlos Rodríguez Gómez (and his ideas about the radical historicity of literature and literary theory), to define the general lines of a new research project. The objective of this new project
Roberto Chuit Roganovich
doaj