Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Lexico-semantic processing in individuals with Alzheimer’s disease: Evidence from picture naming task in Iranian Azerbaijani Turkish-Persian bilinguals [PDF]
نشریه پژوهشهای زبانشناسیAdopting a linguistic approach to the pathology of the mind on bilinguals afflicted with aphasia caused by Alzheimer's disease (AD) has given rise to a wide array of interdisciplinary research in recent years. However, bilinguals’ language impairments in
Maryam Pirzadeh +2 more
doaj +1 more source
DETERMINANTS AND IMPACT OF FINANCIAL SECTOR FDI TO EMERGING [PDF]
This paper reviews the theoretical literature explaining financial FDI, as well as the empirical results on the determinants of financial FDI and its potential effects for the home country.
Alicia Garcia Herrero +1 more
core
Electronic books: Are they effective educational tools for students who are deaf or hard of hearing? [PDF]
, 2016 This literature review will examine the effectiveness of electronic book features on students’ reading development in the general education population and investigate whether or not these digital tools could be a useful tool and/or supplement in literacy
Vaughan, Ainsley
core +1 more source
Classes of exact wavefunctions for general time-dependent Dirac Hamiltonians in 1+1 dimensions
, 2003 In this work we construct two classes of exact solutions for the most general time-dependent Dirac Hamiltonian in 1+1 dimensions. Some problems regarding to some formal solutions in the literature are discussed.
A. de Souza Dutra +16 more
core +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Prediction of Body Image Concern Based on Self-Objectification and Rumination Mediated by Self-Esteem in Women Seeking Cosmetic Surgery [PDF]
مطالعات روانشناختیGiven the increasing trend of cosmetic surgery in Iran and the role of psychological factors in this inclination, the present study aimed to investigate the prediction of body image concern based on self-objectification and rumination, with the mediating
Arefeh Abdollahi Nia +2 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Value Perception of the Chronotope in the Author’s Discourse (Based on the Works of Kazakh Authors)
Open Cultural StudiesThe relevance of the study is due to the increased interest of researchers in the study of the chronotope category in recent decades, and the lack of a unified approach to the analysis of the chronotope in the scientific community.
Zhiyenalina Aizhan +2 more
doaj +1 more source