Results 81 to 90 of about 14,693,831 (281)

Efficiency of mindful self-compassion training on hedonia, autobiographical memory and sleep quality in depressed university students

مجله علوم روانشناختی, 2020
Background: Numerous studies have examined the effectiveness of compassionate education on the conscious mind and the study of pleasure-seeking, historical memory, and sleep quality in depressed individuals.
Adeleh Yousefi Siakoucheh, Seyyed Mousa Kafi Masouleh, Abass Abolghasemi   +2 more
doaj  

Ice Flow Measurements on the East Coast of Lutzow-Holm Bay, Antarctica (Reports of the Japanese Antarctic Research Expedition)

Antarctic Record, 1972
An attempt was made at the measurements of surface velocities of ice flow in several places along the east coast of Lutzow-Holm Bay in 1960 and 1961. Difficulties in preserving stakes and in selecting suitable sites for surveying and the limited time ...
Kenzo FUJIWARA, Yoshio YOSHIDA
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Antoine Sénanque: When the pen reveals the secrets of the stethoscope

Dialogues in Health
Purpose: This article investigates the narrative work of neurologist and novelist Antoine Sénanque by situating it at the intersection of medical practice, literary fiction, and social justice.
El Gaoual Ilham, Taib Berkane, Essarraje Jamal Dine   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Integrative literature review: a research method to incorporate evidence in health care and nursing

, 2008
Evidence based practice is an approach that encourages the development and/or use of research results in clinical practice. Due to the quantity and complexity of information in health care, literature review methods need to be produced.
Karina Dal Sasso Mendes, Renata Cristina de Campos Pereira Silveira, C. Galvão   +2 more
semanticscholar   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Lexico-semantic processing in individuals with Alzheimer’s disease: Evidence from picture naming task in Iranian Azerbaijani Turkish-Persian bilinguals [PDF]

نشریه پژوهش‌های زبان‌شناسی
Adopting a linguistic approach to the pathology of the mind on bilinguals afflicted with aphasia caused by Alzheimer's disease (AD) has given rise to a wide array of interdisciplinary research in recent years. However, bilinguals’ language impairments in
Maryam Pirzadeh, Ramin Golshaie, Mohammad Momenian   +2 more
doaj   +1 more source