Results 61 to 70 of about 14,693,831 (281)

Applied Psychometrics: Sample Size and Sample Power Considerations in Factor Analysis (EFA, CFA) and SEM in General

open access: yes, 2018
Adequate statistical power contributes to observing true relationships in a dataset. With a thoughtful power analysis, the adequate but not excessive sample could be detected.
Theodoros Kyriazos
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Gender-and Age-based Study of “Taboo Words” in the Speech of Persian Speakers [PDF]

open access: yesزبان پژوهی
Language, as a means of communication, is continually influenced by our society, which is why the reflection of social variables in our everyday speech is inevitable.
Zahra Khaleqi, َAva Imani
doaj   +1 more source

Developing cultural competence in general practitioners: an integrative review of the literature

open access: yesBMC Family Practice, 2016
BackgroundCultural competence is a broad concept with multiple theoretical underpinnings and conflicting opinions on how it should be materialized. While it is recognized that cultural competence should be an integral part of General Practice, literature
Kelly Watt, P. Abbott, J. Reath
semanticscholar   +1 more source

LitCovid: an open database of COVID-19 literature

open access: yesNucleic Acids Res., 2020
Since the outbreak of the current pandemic in 2020, there has been a rapid growth of published articles on COVID-19 and SARS-CoV-2, with about 10 000 new articles added each month.
Qingyu Chen, Alexis Allot, Zhiyong Lu
semanticscholar   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Theory of mind and its neural mechanisms: A case study of Kurdish-Persian congenitally blind children in Ilam city

open access: yesJournal of Basic Research in Medical Sciences, 2018
Introduction: Theory of mind is one of the most important aspects of cognitive faculty. The theory of mind is impaired in individuals who suffer from mental disorders like autistic children.
Shahla Raghibdoust   +2 more
doaj  

3D-printing techniques in a medical setting: a systematic literature review

open access: yesBioMedical Engineering OnLine, 2016
Three-dimensional (3D) printing has numerous applications and has gained much interest in the medical world. The constantly improving quality of 3D-printing applications has contributed to their increased use on patients.
P. Tack   +3 more
semanticscholar   +1 more source

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